TY - JOUR
T1 - Systems Biology Graphical Notation
T2 - Entity Relationship language Level 1 Version 2
AU - Sorokin, Anatoly
AU - Le Novère, Nicolas
AU - Luna, Augustin
AU - Czauderna, Tobias
AU - Demir, Emek
AU - Haw, Robin
AU - Mi, Huaiyu
AU - Moodie, Stuart
AU - Schreiber, Falk
AU - Villéger, Alice
PY - 2015
Y1 - 2015
N2 - The Systems Biological Graphical Notation (SBGN) is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD), Entity Relationship (ER) and Activity Flow (AF), allow for the representation of different aspects of biological and biochemical systems at different levels of detail. The SBGN Entity Relationship language (ER) represents biological entities and their interactions and relationships within a network. SBGN ER focuses on all potential relationships between entities without considering temporal aspects. The nodes (elements) describe biological entities, such as proteins and complexes. The edges (connections) provide descriptions of interactions and relationships (or influences), e.g., complex formation, stimulation and inhibition. Among all three languages of SBGN, ER is the closest to protein interaction networks in biological literature and textbooks, but its well-defined semantics offer a superior precision in expressing biological knowledge.
AB - The Systems Biological Graphical Notation (SBGN) is an international community effort for standardized graphical representations of biological pathways and networks. The goal of SBGN is to provide unambiguous pathway and network maps for readers with different scientific backgrounds as well as to support efficient and accurate exchange of biological knowledge between different research communities, industry, and other players in systems biology. Three SBGN languages, Process Description (PD), Entity Relationship (ER) and Activity Flow (AF), allow for the representation of different aspects of biological and biochemical systems at different levels of detail. The SBGN Entity Relationship language (ER) represents biological entities and their interactions and relationships within a network. SBGN ER focuses on all potential relationships between entities without considering temporal aspects. The nodes (elements) describe biological entities, such as proteins and complexes. The edges (connections) provide descriptions of interactions and relationships (or influences), e.g., complex formation, stimulation and inhibition. Among all three languages of SBGN, ER is the closest to protein interaction networks in biological literature and textbooks, but its well-defined semantics offer a superior precision in expressing biological knowledge.
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U2 - 10.2390/biecoll-jib-2015-264
DO - 10.2390/biecoll-jib-2015-264
M3 - Article
C2 - 26528562
AN - SCOPUS:84982174883
SN - 1613-4516
VL - 12
SP - 264
JO - Journal of integrative bioinformatics
JF - Journal of integrative bioinformatics
IS - 2
ER -