Abstract
The effects of TRAIL at various physiological levels were studied on 101/Hf and C3H/Sn mice during acute γ-irradiation with 750 R. An intravenous injection of TRAIL attenuated the effects of γ-irradiation on the body weight, subfractions of blood plasma, horizontal and vertical activity in the open-field test, tissue injury in the small intestine and liver, and content of Hassall's corpuscles in the thymus. The degree of these changes differed in mice of study strains.
Original language | English (US) |
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Pages (from-to) | 452-456 |
Number of pages | 5 |
Journal | Bulletin of Experimental Biology and Medicine |
Volume | 156 |
Issue number | 4 |
DOIs | |
State | Published - Feb 2014 |
Keywords
- TRAIL
- apoptosis
- mice
- radioresistance
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology