Synthesis of nucleoside-based antiviral drugs in ionic liquids

Vineet Kumar, Sanjay V. Malhotra

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Nucleoside-based antiviral drugs have been synthesized using imidazolium-based ionic liquids as reaction medium. The ionic liquids were proved to be better solvents for all the nucleoside in terms of solubility and reaction medium as compared to conventional molecular solvents.

Original languageEnglish (US)
Pages (from-to)5640-5642
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume18
Issue number20
DOIs
StatePublished - Oct 15 2008
Externally publishedYes

Keywords

  • Antiviral drugs
  • HIV
  • HSV
  • Ionic liquid
  • Nucleoside

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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