Synthesis and characterization of a functionalized chiral biaryl capable of exhibiting unidirectional bond rotation

Bart J. Dahl, Bruce P. Branchaud

Research output: Contribution to journalArticle

18 Scopus citations


A class of chiral biaryl molecules that have been designed to undergo unidirectional rotation about the aryl-aryl bond may show promise for future application in the area of synthetic molecular motors. These asymmetric molecules should be capable of channeling chemical energy into repeated 360° rotation in one direction. Herein we report the synthesis and characterization of one such biaryl molecule (1).

Original languageEnglish (US)
Pages (from-to)9599-9602
Number of pages4
JournalTetrahedron Letters
Issue number52
StatePublished - Dec 20 2004



  • Directed bond rotation
  • Molecular motors
  • Nanomachines

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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