Synovial Iron Deposition in Rheumatoid Arthritis

Robert M. Bennett, E. D. Williams, S. M. Lewis, P. J.L. Holt

    Research output: Contribution to journalArticle

    16 Scopus citations

    Abstract

    An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.

    Original languageEnglish (US)
    Pages (from-to)298-304
    Number of pages7
    JournalArthritis & Rheumatism
    Volume16
    Issue number3
    DOIs
    StatePublished - Jan 1 1973

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Rheumatology
    • Immunology
    • Pharmacology (medical)

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  • Cite this

    Bennett, R. M., Williams, E. D., Lewis, S. M., & Holt, P. J. L. (1973). Synovial Iron Deposition in Rheumatoid Arthritis. Arthritis & Rheumatism, 16(3), 298-304. https://doi.org/10.1002/art.1780160303