Synovial Iron Deposition in Rheumatoid Arthritis

Robert M. Bennett, E. D. Williams, S. M. Lewis, P. J.L. Holt

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.

Original languageEnglish (US)
Pages (from-to)298-304
Number of pages7
JournalArthritis & Rheumatism
Volume16
Issue number3
DOIs
StatePublished - 1973
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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