Synovial Iron Deposition in Rheumatoid Arthritis

Robert M. Bennett; E. D. Williams; S. M. Lewis; P. J.L. Holt

doi:10.1002/art.1780160303

Synovial Iron Deposition in Rheumatoid Arthritis

Robert M. Bennett, E. D. Williams, S. M. Lewis, P. J.L. Holt

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19 Scopus citations

Abstract

An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.

Original language	English (US)
Pages (from-to)	298-304
Number of pages	7
Journal	Arthritis & Rheumatism
Volume	16
Issue number	3
DOIs	https://doi.org/10.1002/art.1780160303
State	Published - 1973
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

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abstract = "An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.",

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AU - Williams, E. D.

AU - Lewis, S. M.

AU - Holt, P. J.L.

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AB - An isotope ferrokinetic study has been used to study the rate of iron deposition in 13 rheumatoid knees. Iron accumulation occurred only after incorporation of labelled iron into circulating erythrocytes, suggesting that intermittent intraarticular hemorrhages were the source of the deposits. The mean iron accumulation was 1.25 mg/knee/day representing a mean intraarticular blood loss of 3.58 ml. There was no correlation between the degree of iron deposition and the hemoglobin, platelet count or serum iron.

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Synovial Iron Deposition in Rheumatoid Arthritis

Abstract

ASJC Scopus subject areas

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