Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors

Medicine & Life Sciences

• Proto-Oncogene Proteins c-akt 100%
• Sirolimus 89%
• Protein Kinase Inhibitors 88%
• Phosphatidylinositol 3-Kinase 85%
• Autophagy 80%
• Glioma 77%
• TOR Serine-Threonine Kinases 56%
• 7-hydroxystaurosporine 42%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 20%
• Phosphotransferases 6%
• Phosphorylation 5%
• Cell Proliferation 5%
• Neoplasms 5%
• Apoptosis 5%
• Therapeutics 1%