Symptomatic Calcification of Subureteral Collagen Ten Years After Injection

Kenneth G. Nepple, Matthew J. Knudson, Christopher S. Cooper, J. Christopher Austin

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Bovine glutaraldehyde cross-linked collagen is an injectable bulking agent used to treat urinary incontinence and vesicoureteral reflux. A 16-year-old girl had previously undergone left subureteral injection of collagen at the age of 6 years. She presented to our clinic after passing a 7-mm calcification with a history of hematuria and intermittent back pain. Computed tomography showed two hyperdense foci measuring 2 mm each in the region of the left ureterovesical junction that did not change on follow-up imaging. On cystoscopy, two submucosal calcifications were located medially and inferiorly to the left ureteral orifice and were removed endoscopically.

Original languageEnglish (US)
Pages (from-to)982.e1-982.e2
Issue number5
StatePublished - May 2007
Externally publishedYes

ASJC Scopus subject areas

  • Urology


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