Symptom Trajectories after an Emergency Department Visit for Potential Acute Coronary Syndrome

Elizabeth Knight, Kimberly Shea, Anne G. Rosenfeld, Sarah Schmiege, Chiu Hsieh Hsu, Holli A. Devon

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background Many patients evaluated for acute coronary syndrome (ACS) in emergency departments (EDs) continue to experience troubling symptoms after discharge-regardless of their ultimate medical diagnosis. However, comprehensive understanding of common post-ED symptom trajectories is lacking. Objectives The aim of this study was to identify common trajectories of symptom severity in the 6 months after an ED visit for potential ACS. Methods This was a secondary analysis of data from a larger observational, prospective study conducted in five U.S. EDs. Patients (N = 1005) who had electrocardiogram and biomarker testing ordered, and were identified by the triage nurse as potentially having ACS, were enrolled. Symptom severity was assessed in the hospital after initial stabilization and by telephone at 30 days and 6 months using the validated 13-item ACS Symptom Checklist. Growth mixture modeling was used for the secondary analysis. The eight most commonly reported symptoms (chest discomfort, chest pain, chest pressure, light-headedness, shortness of breath, shoulder pain, unusual fatigue, and upper back pain) were modeled across the three study time points. Models with increasing numbers of classes were compared, and final model selection was based on a combination of interpretability, theoretical justification, and statistical fit indices. Results The sample was 62.6% male with a mean age of 60.2 years (SD = 14.17 years), and 57.1% ruled out for ACS. Between two and four distinct trajectory classes were identified for each symptom. The seven different types of trajectories identified across the eight symptoms were labeled tapering off, mild/persistent, moderate/persistent, moderate/worsening, moderate/improving, late onset, and severe/improving. Trajectories differed on age, gender, and diagnosis. Discussion Research on the individual nature of symptom trajectories can contribute to patient-centered, rather than disease-centered, care. Further research is needed to verify the existence of multiple symptoms trajectories in diverse populations and to assess the antecedents and consequences of individual symptom trajectories.

Original languageEnglish (US)
Pages (from-to)268-278
Number of pages11
JournalNursing research
Volume65
Issue number4
DOIs
StatePublished - Jul 1 2016
Externally publishedYes

Fingerprint

Acute Coronary Syndrome
Hospital Emergency Service
Thorax
Shoulder Pain
Triage
Dizziness
Back Pain
Checklist
Chest Pain
Research
Telephone
Dyspnea
Observational Studies
Fatigue
Electrocardiography
Biomarkers
Nurses
Prospective Studies
Pressure
Growth

Keywords

  • acute coronary syndrome
  • growth mixture model
  • health trajectories
  • hospital emergency service
  • longitudinal studies
  • symptom assessment

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Symptom Trajectories after an Emergency Department Visit for Potential Acute Coronary Syndrome. / Knight, Elizabeth; Shea, Kimberly; Rosenfeld, Anne G.; Schmiege, Sarah; Hsu, Chiu Hsieh; Devon, Holli A.

In: Nursing research, Vol. 65, No. 4, 01.07.2016, p. 268-278.

Research output: Contribution to journalArticle

Knight, Elizabeth ; Shea, Kimberly ; Rosenfeld, Anne G. ; Schmiege, Sarah ; Hsu, Chiu Hsieh ; Devon, Holli A. / Symptom Trajectories after an Emergency Department Visit for Potential Acute Coronary Syndrome. In: Nursing research. 2016 ; Vol. 65, No. 4. pp. 268-278.
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abstract = "Background Many patients evaluated for acute coronary syndrome (ACS) in emergency departments (EDs) continue to experience troubling symptoms after discharge-regardless of their ultimate medical diagnosis. However, comprehensive understanding of common post-ED symptom trajectories is lacking. Objectives The aim of this study was to identify common trajectories of symptom severity in the 6 months after an ED visit for potential ACS. Methods This was a secondary analysis of data from a larger observational, prospective study conducted in five U.S. EDs. Patients (N = 1005) who had electrocardiogram and biomarker testing ordered, and were identified by the triage nurse as potentially having ACS, were enrolled. Symptom severity was assessed in the hospital after initial stabilization and by telephone at 30 days and 6 months using the validated 13-item ACS Symptom Checklist. Growth mixture modeling was used for the secondary analysis. The eight most commonly reported symptoms (chest discomfort, chest pain, chest pressure, light-headedness, shortness of breath, shoulder pain, unusual fatigue, and upper back pain) were modeled across the three study time points. Models with increasing numbers of classes were compared, and final model selection was based on a combination of interpretability, theoretical justification, and statistical fit indices. Results The sample was 62.6{\%} male with a mean age of 60.2 years (SD = 14.17 years), and 57.1{\%} ruled out for ACS. Between two and four distinct trajectory classes were identified for each symptom. The seven different types of trajectories identified across the eight symptoms were labeled tapering off, mild/persistent, moderate/persistent, moderate/worsening, moderate/improving, late onset, and severe/improving. Trajectories differed on age, gender, and diagnosis. Discussion Research on the individual nature of symptom trajectories can contribute to patient-centered, rather than disease-centered, care. Further research is needed to verify the existence of multiple symptoms trajectories in diverse populations and to assess the antecedents and consequences of individual symptom trajectories.",
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AU - Shea, Kimberly

AU - Rosenfeld, Anne G.

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AU - Hsu, Chiu Hsieh

AU - Devon, Holli A.

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AB - Background Many patients evaluated for acute coronary syndrome (ACS) in emergency departments (EDs) continue to experience troubling symptoms after discharge-regardless of their ultimate medical diagnosis. However, comprehensive understanding of common post-ED symptom trajectories is lacking. Objectives The aim of this study was to identify common trajectories of symptom severity in the 6 months after an ED visit for potential ACS. Methods This was a secondary analysis of data from a larger observational, prospective study conducted in five U.S. EDs. Patients (N = 1005) who had electrocardiogram and biomarker testing ordered, and were identified by the triage nurse as potentially having ACS, were enrolled. Symptom severity was assessed in the hospital after initial stabilization and by telephone at 30 days and 6 months using the validated 13-item ACS Symptom Checklist. Growth mixture modeling was used for the secondary analysis. The eight most commonly reported symptoms (chest discomfort, chest pain, chest pressure, light-headedness, shortness of breath, shoulder pain, unusual fatigue, and upper back pain) were modeled across the three study time points. Models with increasing numbers of classes were compared, and final model selection was based on a combination of interpretability, theoretical justification, and statistical fit indices. Results The sample was 62.6% male with a mean age of 60.2 years (SD = 14.17 years), and 57.1% ruled out for ACS. Between two and four distinct trajectory classes were identified for each symptom. The seven different types of trajectories identified across the eight symptoms were labeled tapering off, mild/persistent, moderate/persistent, moderate/worsening, moderate/improving, late onset, and severe/improving. Trajectories differed on age, gender, and diagnosis. Discussion Research on the individual nature of symptom trajectories can contribute to patient-centered, rather than disease-centered, care. Further research is needed to verify the existence of multiple symptoms trajectories in diverse populations and to assess the antecedents and consequences of individual symptom trajectories.

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KW - longitudinal studies

KW - symptom assessment

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