Survey of practice patterns and preparedness for endovascular therapy in acute pediatric stroke

Jenny L. Wilson, Catherine Amlie-Lefond, Todd Abruzzo, Darren B. Orbach, Michael J. Rivkin, Gabrielle A. deVeber, Paola Pergami

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Purpose: Endovascular therapy benefits selected adults with acute stroke while data are lacking for children. The purpose of this study was to assess physician practice and institutional preparedness for endovascular therapy in pediatric stroke. Methods: A link to an anonymous online survey was sent to members of the International Pediatric Stroke Study (IPSS) group about physician experience with endovascular therapy, likelihood of treatment for provided clinical vignettes, and institutional readiness for the delivery of endovascular therapy to children. Results: Thirty-one pediatric physicians with a mean of 11 years (SD 7.1) of experience responded. All but two would consider endovascular therapy in a child, and 20 (64.5%) had recommended endovascular therapy for a child in the preceding year. Most (n = 19, 67.9%) did not commit to an age minimum for endovascular therapy. Sixteen (57.1%) would consider treatment up to 24 h after symptom onset with 19 (67.9%) respondents reporting that their practice changed after the 2018 American Heart Association guidelines extended the time window for endovascular therapy in adults. Seventeen (60.7%) preferred imaging that included perfusion in children presenting beyond 6 h. Nineteen (70.4%) had institutional endovascular therapy criteria. Physicians in larger pediatric groups had more “likely to treat” responses on the clinical vignettes than physicians working in smaller groups (11.7 vs. 6.1, p < 0.05). Conclusion: Pediatric stroke physicians are largely willing to consider endovascular therapy with most changing their practice according to adult guidelines, though experience and selection criteria varied. These findings may help to inform consensus guidelines and clinical trial development.

Original languageEnglish (US)
Pages (from-to)2371-2378
Number of pages8
JournalChild's Nervous System
Issue number12
StatePublished - Dec 1 2019


  • Childhood stroke
  • Critical care
  • Embolism
  • Endovascular therapy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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