TY - JOUR
T1 - Surveillance of extrapulmonary nontuberculous mycobacteria infections, Oregon, USA, 2007–2012
AU - Henkle, Emily
AU - Hedberg, Katrina
AU - Schafer, Sean D.
AU - Winthrop, Kevin L.
N1 - Funding Information:
This study was supported by the University of Rochester Respiratory Pathogens Research Center/National Institute of Allergy and Infectious Disease (HHSN272201200005C).
Publisher Copyright:
© 2017, Centers for Disease Control and Prevention (CDC). All rights reserved.
PY - 2017/10
Y1 - 2017/10
N2 - Limited data are available describing extrapulmonary nontuberculous mycobacteria (NTM) infections in the general population. We describe results from statewide population-based laboratory surveillance in Oregon, USA, during 2007–2012. We defined a case of extrapulmonary NTM infection as >1 isolate from skin/soft tissue, disseminated sites, lymph node, joint, or other sites. The annual incidence of extrapulmonary NTM infection (other than Mycobacterium gordonae) was stable, averaging 1.5 cases/100,000 population. Median age of the 334 patients was 51 years, and 53% of patients were female. Half of cases were caused by M. avium complex, but rapid-growing NTM species accounted for one third of cases. Most extrapulmonary NTM infections are skin/soft tissue. Compared with pulmonary NTM infection, more extrapulmonary infections are caused by rapid-growing NTM species. The designation of NTM as a reportable disease in Oregon in 2014 will result in better detection of changes in the incidence and patterns of disease in the future.
AB - Limited data are available describing extrapulmonary nontuberculous mycobacteria (NTM) infections in the general population. We describe results from statewide population-based laboratory surveillance in Oregon, USA, during 2007–2012. We defined a case of extrapulmonary NTM infection as >1 isolate from skin/soft tissue, disseminated sites, lymph node, joint, or other sites. The annual incidence of extrapulmonary NTM infection (other than Mycobacterium gordonae) was stable, averaging 1.5 cases/100,000 population. Median age of the 334 patients was 51 years, and 53% of patients were female. Half of cases were caused by M. avium complex, but rapid-growing NTM species accounted for one third of cases. Most extrapulmonary NTM infections are skin/soft tissue. Compared with pulmonary NTM infection, more extrapulmonary infections are caused by rapid-growing NTM species. The designation of NTM as a reportable disease in Oregon in 2014 will result in better detection of changes in the incidence and patterns of disease in the future.
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U2 - 10.3201/eid2310.170845
DO - 10.3201/eid2310.170845
M3 - Article
C2 - 28930014
AN - SCOPUS:85029754422
SN - 1080-6040
VL - 23
SP - 1627
EP - 1630
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 10
ER -