Abstract
Neuroendocrine tumors of the small bowel are rare, slow-growing malignancies that commonly metastasize to nodes at the root of the mesentery and the liver. Liver metastases are associated with carcinoid syndrome. Mesenteric nodal masses can cause bowel obstruction, intestinal angina, or variceal hemorrhage. Patients die of liver failure or bowel obstruction. Primary resection is associated with improved survival rates. Selected patients may benefit from liver debulking operations. Liver resection has excellent survival rates even in the event of an incomplete resection, as well as improvement in hormonal symptoms. Radiofrequency ablation can help to preserve hepatic parenchyma during resection.
Original language | English (US) |
---|---|
Pages (from-to) | 49-61 |
Number of pages | 13 |
Journal | Hematology/Oncology Clinics of North America |
Volume | 30 |
Issue number | 1 |
DOIs | |
State | Published - Feb 1 2016 |
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Keywords
- Ablation
- Liver
- Mesenteric nodal mass
- Metastasis
- Neuroendocrine
- Primary tumor
- Resection
ASJC Scopus subject areas
- Oncology
- Hematology
Cite this
Surgical Treatment of Small Bowel Neuroendocrine Tumors. / Farley, Heather A.; Pommier, Rodney.
In: Hematology/Oncology Clinics of North America, Vol. 30, No. 1, 01.02.2016, p. 49-61.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Surgical Treatment of Small Bowel Neuroendocrine Tumors
AU - Farley, Heather A.
AU - Pommier, Rodney
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Neuroendocrine tumors of the small bowel are rare, slow-growing malignancies that commonly metastasize to nodes at the root of the mesentery and the liver. Liver metastases are associated with carcinoid syndrome. Mesenteric nodal masses can cause bowel obstruction, intestinal angina, or variceal hemorrhage. Patients die of liver failure or bowel obstruction. Primary resection is associated with improved survival rates. Selected patients may benefit from liver debulking operations. Liver resection has excellent survival rates even in the event of an incomplete resection, as well as improvement in hormonal symptoms. Radiofrequency ablation can help to preserve hepatic parenchyma during resection.
AB - Neuroendocrine tumors of the small bowel are rare, slow-growing malignancies that commonly metastasize to nodes at the root of the mesentery and the liver. Liver metastases are associated with carcinoid syndrome. Mesenteric nodal masses can cause bowel obstruction, intestinal angina, or variceal hemorrhage. Patients die of liver failure or bowel obstruction. Primary resection is associated with improved survival rates. Selected patients may benefit from liver debulking operations. Liver resection has excellent survival rates even in the event of an incomplete resection, as well as improvement in hormonal symptoms. Radiofrequency ablation can help to preserve hepatic parenchyma during resection.
KW - Ablation
KW - Liver
KW - Mesenteric nodal mass
KW - Metastasis
KW - Neuroendocrine
KW - Primary tumor
KW - Resection
UR - http://www.scopus.com/inward/record.url?scp=84955078337&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955078337&partnerID=8YFLogxK
U2 - 10.1016/j.hoc.2015.09.001
DO - 10.1016/j.hoc.2015.09.001
M3 - Article
C2 - 26614368
AN - SCOPUS:84955078337
VL - 30
SP - 49
EP - 61
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
SN - 0889-8588
IS - 1
ER -