Surgical treatment of myasthenia gravis in childhood

John R. Campbell, James M. Bisio, Marvin W. Harrison, Timothy J. Campbell

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Myasthenia gravis is considered to be an autoimmune disorder of neuromuscular transmission. Thymectomy is an effective mode of treatment which produces either remission or stabilization of symptoms especially in young female patients with short duration of disease. The present study, records the experience in ten pediatric patients with early thymectomy done via the transcervical approach. There were no operative deaths or serious complications. Follow-up for a mean of 37 months has shown one to be in complete remission requiring no medication and eight to have improved or stable symptoms. Thymectomy via the transcervical approach is an effective mode of treatment for patients with myasthenia gravis. Since this approach involves a small dissection and avoids sternotomy, the transcervical approach results in a very short postoperative recovery period. It is ideal for those patients not in respiratory failure. It can also be safely done in patients requiring intubation for acute respiratory failure preoperatively.

Original languageEnglish (US)
Pages (from-to)857-861
Number of pages5
JournalJournal of Pediatric Surgery
Volume18
Issue number6
DOIs
StatePublished - 1983

Fingerprint

Myasthenia Gravis
Thymectomy
Respiratory Insufficiency
Neuromuscular Junction Diseases
Therapeutics
Sternotomy
Postoperative Period
Intubation
Dissection
Pediatrics

Keywords

  • Myasthenia gravis
  • thymectomy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Campbell, J. R., Bisio, J. M., Harrison, M. W., & Campbell, T. J. (1983). Surgical treatment of myasthenia gravis in childhood. Journal of Pediatric Surgery, 18(6), 857-861. https://doi.org/10.1016/S0022-3468(83)80037-2

Surgical treatment of myasthenia gravis in childhood. / Campbell, John R.; Bisio, James M.; Harrison, Marvin W.; Campbell, Timothy J.

In: Journal of Pediatric Surgery, Vol. 18, No. 6, 1983, p. 857-861.

Research output: Contribution to journalArticle

Campbell, JR, Bisio, JM, Harrison, MW & Campbell, TJ 1983, 'Surgical treatment of myasthenia gravis in childhood', Journal of Pediatric Surgery, vol. 18, no. 6, pp. 857-861. https://doi.org/10.1016/S0022-3468(83)80037-2
Campbell, John R. ; Bisio, James M. ; Harrison, Marvin W. ; Campbell, Timothy J. / Surgical treatment of myasthenia gravis in childhood. In: Journal of Pediatric Surgery. 1983 ; Vol. 18, No. 6. pp. 857-861.
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