Surgeon leadership enables development of a colorectal cancer biorepository

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: We hypothesized that surgeons can improve the collection of all necessary elements (tissue and clinical data) needed to build a complete, robust research biorepository. Methods: All colorectal cancer patients treated at a university medical center and its affiliates were eligible for inclusion. Data were collected from an 18-page personal and family health questionnaire, a prospectively maintained clinical database, and molecular testing. Tissues included serum, plasma and peripheral blood mononuclear cells, and tumor and normal tissue. We compared 2 groups: the surgeon-referred group and the other clinician-referred group. The primary outcome was the complete collection of data (ie, preoperative/staging clinical data, blood samples, and tissue collection). Statistical analysis was performed using the Student t test. Results: Since 2006, 452 patients were approached, and 430 (95%) have been enrolled. Of these, 124 were referred by their surgeon, and 306 were consented in a clinic or over the telephone. Of patients referred by their surgeon, tumor tissue, blood samples, and preoperative/staging clinical data were obtained in 119 patients; conversely, in patients referred by oncologists or other clinicians, only 133 patients had complete data (96% vs 43.5%, P

Original languageEnglish (US)
Pages (from-to)563-565
Number of pages3
JournalAmerican Journal of Surgery
Volume205
Issue number5
DOIs
StatePublished - May 2013

Fingerprint

Colorectal Neoplasms
Chemical Databases
Family Health
Telephone
Surgeons
Blood Cells
Neoplasms
Students
Serum
Research

Keywords

  • Biorepository
  • Colon cancer
  • Rectal cancer
  • Registry
  • Tissue bank

ASJC Scopus subject areas

  • Surgery

Cite this

Surgeon leadership enables development of a colorectal cancer biorepository. / Tsikitis, Vassiliki; Lu, Kim; Douthit, Miriam; Herzig, Daniel.

In: American Journal of Surgery, Vol. 205, No. 5, 05.2013, p. 563-565.

Research output: Contribution to journalArticle

@article{58f7d401fae446cfadc1d7bd4b5505e4,
title = "Surgeon leadership enables development of a colorectal cancer biorepository",
abstract = "Background: We hypothesized that surgeons can improve the collection of all necessary elements (tissue and clinical data) needed to build a complete, robust research biorepository. Methods: All colorectal cancer patients treated at a university medical center and its affiliates were eligible for inclusion. Data were collected from an 18-page personal and family health questionnaire, a prospectively maintained clinical database, and molecular testing. Tissues included serum, plasma and peripheral blood mononuclear cells, and tumor and normal tissue. We compared 2 groups: the surgeon-referred group and the other clinician-referred group. The primary outcome was the complete collection of data (ie, preoperative/staging clinical data, blood samples, and tissue collection). Statistical analysis was performed using the Student t test. Results: Since 2006, 452 patients were approached, and 430 (95{\%}) have been enrolled. Of these, 124 were referred by their surgeon, and 306 were consented in a clinic or over the telephone. Of patients referred by their surgeon, tumor tissue, blood samples, and preoperative/staging clinical data were obtained in 119 patients; conversely, in patients referred by oncologists or other clinicians, only 133 patients had complete data (96{\%} vs 43.5{\%}, P",
keywords = "Biorepository, Colon cancer, Rectal cancer, Registry, Tissue bank",
author = "Vassiliki Tsikitis and Kim Lu and Miriam Douthit and Daniel Herzig",
year = "2013",
month = "5",
doi = "10.1016/j.amjsurg.2013.01.020",
language = "English (US)",
volume = "205",
pages = "563--565",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Surgeon leadership enables development of a colorectal cancer biorepository

AU - Tsikitis, Vassiliki

AU - Lu, Kim

AU - Douthit, Miriam

AU - Herzig, Daniel

PY - 2013/5

Y1 - 2013/5

N2 - Background: We hypothesized that surgeons can improve the collection of all necessary elements (tissue and clinical data) needed to build a complete, robust research biorepository. Methods: All colorectal cancer patients treated at a university medical center and its affiliates were eligible for inclusion. Data were collected from an 18-page personal and family health questionnaire, a prospectively maintained clinical database, and molecular testing. Tissues included serum, plasma and peripheral blood mononuclear cells, and tumor and normal tissue. We compared 2 groups: the surgeon-referred group and the other clinician-referred group. The primary outcome was the complete collection of data (ie, preoperative/staging clinical data, blood samples, and tissue collection). Statistical analysis was performed using the Student t test. Results: Since 2006, 452 patients were approached, and 430 (95%) have been enrolled. Of these, 124 were referred by their surgeon, and 306 were consented in a clinic or over the telephone. Of patients referred by their surgeon, tumor tissue, blood samples, and preoperative/staging clinical data were obtained in 119 patients; conversely, in patients referred by oncologists or other clinicians, only 133 patients had complete data (96% vs 43.5%, P

AB - Background: We hypothesized that surgeons can improve the collection of all necessary elements (tissue and clinical data) needed to build a complete, robust research biorepository. Methods: All colorectal cancer patients treated at a university medical center and its affiliates were eligible for inclusion. Data were collected from an 18-page personal and family health questionnaire, a prospectively maintained clinical database, and molecular testing. Tissues included serum, plasma and peripheral blood mononuclear cells, and tumor and normal tissue. We compared 2 groups: the surgeon-referred group and the other clinician-referred group. The primary outcome was the complete collection of data (ie, preoperative/staging clinical data, blood samples, and tissue collection). Statistical analysis was performed using the Student t test. Results: Since 2006, 452 patients were approached, and 430 (95%) have been enrolled. Of these, 124 were referred by their surgeon, and 306 were consented in a clinic or over the telephone. Of patients referred by their surgeon, tumor tissue, blood samples, and preoperative/staging clinical data were obtained in 119 patients; conversely, in patients referred by oncologists or other clinicians, only 133 patients had complete data (96% vs 43.5%, P

KW - Biorepository

KW - Colon cancer

KW - Rectal cancer

KW - Registry

KW - Tissue bank

UR - http://www.scopus.com/inward/record.url?scp=84876227855&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84876227855&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2013.01.020

DO - 10.1016/j.amjsurg.2013.01.020

M3 - Article

VL - 205

SP - 563

EP - 565

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 5

ER -