Surface cell morphology of the anesthetic human cornea: A color specular microscopic study

M. A. Lemp, William Mathers, J. B. Gold

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function.

Original languageEnglish (US)
Pages (from-to)102-107
Number of pages6
JournalActa Ophthalmologica
Volume67
Issue numberSUPPL. 192
StatePublished - 1989
Externally publishedYes

Fingerprint

Cornea
Anesthetics
Color
Rose Bengal
Cell Size
Microscopy
Anesthesia
Epithelial Cells
Maintenance
Staining and Labeling

ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Surface cell morphology of the anesthetic human cornea : A color specular microscopic study. / Lemp, M. A.; Mathers, William; Gold, J. B.

In: Acta Ophthalmologica, Vol. 67, No. SUPPL. 192, 1989, p. 102-107.

Research output: Contribution to journalArticle

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