Surface cell morphology of the anesthetic human cornea: A color specular microscopic study

Michael A. Lemp, William D. Mathers, Joseph B. Gold

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Abstract The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function. 1989 Institution Acta Ophthalmologica Scandinavica

Original languageEnglish (US)
Pages (from-to)102-107
Number of pages6
JournalActa ophthalmologica
Volume67
Issue number192 S
DOIs
StatePublished - May 1989

Keywords

  • Corneal epithelium
  • corneal anesthesia
  • morphology
  • specular microscopy

ASJC Scopus subject areas

  • Ophthalmology

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