Surface cell morphology of the anesthetic human cornea: A color specular microscopic study

Michael A. Lemp; William D. Mathers; Joseph B. Gold

doi:10.1111/j.1755-3768.1989.tb07101.x

Surface cell morphology of the anesthetic human cornea: A color specular microscopic study

Michael A. Lemp, William D. Mathers, Joseph B. Gold

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Abstract The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function. 1989 Institution Acta Ophthalmologica Scandinavica

Original language	English (US)
Pages (from-to)	102-107
Number of pages	6
Journal	Acta ophthalmologica
Volume	67
Issue number	192 S
DOIs	https://doi.org/10.1111/j.1755-3768.1989.tb07101.x
State	Published - May 1989
Externally published	Yes

Keywords

Corneal epithelium
corneal anesthesia
morphology
specular microscopy

ASJC Scopus subject areas

Ophthalmology

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10.1111/j.1755-3768.1989.tb07101.x

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title = "Surface cell morphology of the anesthetic human cornea: A color specular microscopic study",

abstract = "Abstract The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function. 1989 Institution Acta Ophthalmologica Scandinavica",

keywords = "Corneal epithelium, corneal anesthesia, morphology, specular microscopy",

author = "Lemp, {Michael A.} and Mathers, {William D.} and Gold, {Joseph B.}",

year = "1989",

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doi = "10.1111/j.1755-3768.1989.tb07101.x",

language = "English (US)",

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T2 - A color specular microscopic study

AU - Lemp, Michael A.

AU - Mathers, William D.

AU - Gold, Joseph B.

PY - 1989/5

Y1 - 1989/5

N2 - Abstract The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function. 1989 Institution Acta Ophthalmologica Scandinavica

AB - Abstract The technique of color specular microscopy has been utilized to study the surface cell morphology of the human cornea in 6 subjects with profound corneal anesthesia from diverse causes. In an analysis of cell area, perimeter, and shape, anesthetic corneas showed a statistically significant increase in cell size and perimeter. In addition, there was a loss of cellular outlines and overall increase in rose bengal staining of cells. We believe that these cellular microscopic changes reflect profound changes in epithelial cell turnover related to a decrease in neurohumoral transmitters known to be necessary for maintenance of normal corneal morphology and function. 1989 Institution Acta Ophthalmologica Scandinavica

KW - Corneal epithelium

KW - corneal anesthesia

KW - morphology

KW - specular microscopy

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ER -

Surface cell morphology of the anesthetic human cornea: A color specular microscopic study

Abstract

Keywords

ASJC Scopus subject areas

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