Abstract
Sugammadex has been used clinically since 2008, and it represents the only cyclodextrin neuromuscular blocking reversal agent currently available for patient care. Sugammadex's unique mechanism of action allows it to reverse the effects of aminosteroid neuromuscular blockade rapidly, and pharmacodynamically predictable doses are selected based on quantitative neuromuscular monitoring. The drug has several potential adverse effects, predominantly related to immediate hypersensitivity reactions and bradyarrhythmias, and it can be costly. Overall, when employed appropriately, it represents an efficacious addition to the perioperative pharmaceutical armamentarium with significant utility.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 133-140 |
| Number of pages | 8 |
| Journal | AANA journal |
| Volume | 90 |
| Issue number | 2 |
| State | Published - Apr 1 2022 |
| Externally published | Yes |
Keywords
- Anesthesiology
- neuromuscular block reversal
- reversal agent
- sugammadex
ASJC Scopus subject areas
- Medical–Surgical
- Advanced and Specialized Nursing
- Anesthesiology and Pain Medicine