Successful vaccines

Ian J. Amanna, Mark K. Slifka

    Research output: Chapter in Book/Report/Conference proceedingChapter

    16 Scopus citations


    Vaccines are considered one of the most important advances in modern medicine and have greatly improved our quality of life by reducing or eliminating many serious infectious diseases. Successful vaccines have been developed against many of the most common human pathogens, and this success has not been dependent upon any one specific class of vaccine since subunit vaccines, non-replicating whole-virus or whole-bacteria vaccines, and attenuated live vaccines have all been effective for particular vaccine targets. After completing the initial immunization series, one common aspect of successful vaccines is that they induce long-term protective immunity. In contrast, several partially successful vaccines appear to induce protection that is relatively short-lived and it is likely that long-term protective immunity will be critical for making effective vaccines against our most challenging diseases such as AIDS and malaria.

    Original languageEnglish (US)
    Title of host publicationCurrent Topics in Microbiology and Immunology
    PublisherSpringer Science and Business Media Deutschland GmbH
    Number of pages30
    StatePublished - 2020

    Publication series

    NameCurrent Topics in Microbiology and Immunology
    ISSN (Print)0070-217X
    ISSN (Electronic)2196-9965

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Microbiology
    • Immunology
    • Microbiology (medical)


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