Successful treatment of optic neuropathy in association with systemic lupus erythematosus using intravenous cyclophosphamide

James (Jim) Rosenbaum, Jennifer Simpson, C. Michael Neuwelt

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Background - Optic neuropathy is a rare manifestation of systemic lupus erythematosus (SLE). In a previous series most patients with optic neuropathy in association with SLE had a final visual acuity of 20/200 or less despite corticosteroid therapy. Methods - Three patients (five affected eyes) with severe retrobulbar optic neuropathy in association with SLE were treated promptly with intravenous cyclophosphamide and corticosteroids. Results - All patients recovered excellent visual acuity. Conclusion - Although optic neuropathy in association with SLE might have several different aetiologies, intravenous cyclophosphamide should be strongly considered as a therapeutic alternative.

Original languageEnglish (US)
Pages (from-to)130-132
Number of pages3
JournalBritish Journal of Ophthalmology
Volume81
Issue number2
StatePublished - Feb 1997

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Optic Nerve Diseases
Systemic Lupus Erythematosus
Cyclophosphamide
Visual Acuity
Adrenal Cortex Hormones
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Successful treatment of optic neuropathy in association with systemic lupus erythematosus using intravenous cyclophosphamide. / Rosenbaum, James (Jim); Simpson, Jennifer; Neuwelt, C. Michael.

In: British Journal of Ophthalmology, Vol. 81, No. 2, 02.1997, p. 130-132.

Research output: Contribution to journalArticle

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