Successful treatment of metastatic hormone-refractory prostate cancer with malignant pericardial tamponade using docetaxel

Brandon Hayes-Lattin, Peter A. Kovach, W. David Henner, Tomasz (Tom) Beer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Reports of malignant pericardial effusion due to adenocarcinoma of the prostate are few and describe only patients with hormone-naive disease. We report a case of malignant pleural and pericardial effusions due to metastatic hormone-refractory prostate cancer. Despite presenting with pericardial tamponade, this patient was successfully treated with pericardiocentesis and intrapericardial methylprednisolone and cisplatin, followed by a course of intravenous docetaxel. The patient was alive and free of disease-related symptoms nearly 2 years later. This case suggests that patients with pericardial tamponade due to hormone-refractory prostate cancer do not have a uniformly dismal prognosis and should be considered for aggressive treatment.

Original languageEnglish (US)
JournalUrology
Volume59
Issue number1
StatePublished - 2002

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docetaxel
Cardiac Tamponade
Prostatic Neoplasms
Hormones
Pericardial Effusion
Pericardiocentesis
Malignant Pleural Effusion
Methylprednisolone
Therapeutics
Cisplatin
Prostate
Adenocarcinoma

ASJC Scopus subject areas

  • Urology

Cite this

Successful treatment of metastatic hormone-refractory prostate cancer with malignant pericardial tamponade using docetaxel. / Hayes-Lattin, Brandon; Kovach, Peter A.; Henner, W. David; Beer, Tomasz (Tom).

In: Urology, Vol. 59, No. 1, 2002.

Research output: Contribution to journalArticle

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