Successful treatment of metastatic hormone-refractory prostate cancer with malignant pericardial tamponade using docetaxel

Brandon M. Hayes-Lattin, Peter A. Kovach, W. David Henner, Tomasz M. Beer

Research output: Contribution to journalArticle

3 Scopus citations


Reports of malignant pericardial effusion due to adenocarcinoma of the prostate are few and describe only patients with hormone-naive disease. We report a case of malignant pleural and pericardial effusions due to metastatic hormone-refractory prostate cancer. Despite presenting with pericardial tamponade, this patient was successfully treated with pericardiocentesis and intrapericardial methylprednisolone and cisplatin, followed by a course of intravenous docetaxel. The patient was alive and free of disease-related symptoms nearly 2 years later. This case suggests that patients with pericardial tamponade due to hormone-refractory prostate cancer do not have a uniformly dismal prognosis and should be considered for aggressive treatment.

Original languageEnglish (US)
Number of pages1
Issue number1
StatePublished - Jan 1 2002


ASJC Scopus subject areas

  • Urology

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