Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques

David R. Hout, Melissa L. Gomez, Erik Pacyniak, Lisa M. Gomez, Barbara Fegley, Ellyn R. Mulcahy, M. Sarah Hill, Nathan Culley, David M. Pinson, Warren Nothnick, Michael F. Powers, Scott W. Wong, Edward B. Stephens

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