Subacute, reversible motor neuron disease

Tarvez Tucker, Robert B. Layzer, Robert G. Miller, David Chad

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Four patients with a clinical syndrome closely resembling amyotrophic lateral sclerosis recovered completely, without treatment, 5 to 12 months after onset. Electrodiagnostic tests revealed acute and chronic denervation, with normal motor and sensory nerve conduction studies. The CSF was normal, and tests for paraproteinemia, heavy metal intoxication, and systemic illness were negative. Although such cases are rare, the possibility of spontaneous recovery should always be considered when counseling patients with suspected ALS.

Original languageEnglish (US)
Pages (from-to)1541-1544
Number of pages4
Issue number10
StatePublished - Oct 1991
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology


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