TY - CHAP
T1 - Structure, function, and regulation of the corpus luteum
AU - Stouffer, Richard L.
N1 - Funding Information:
Appreciation is expressed to those who kindled the author's interest in this field: Drs. David Schomberg, Gary Hodgen, Harold Behrman, Ernst Knobil, Gordon Niswender, and Irv Rothchild. Also, the input of other outstanding scientists, especially through their recent, timely reviews as cited in the text, is noted, including Drs. Roger Short, John McCracken, Geula Gibori, Bruce Murphy, Rena Meidan, Jerome Strauss III, David Sherwood, Richard Ivell, Bo Rueda, Jonathan Tilly, Tony Zeleznik, Milo Wiltbank, Mats Brannstrom, and Fuller Bazer. Owing to space limitations, many appropriate references could not be included; the reader is encouraged to read other timely and historical reviews, plus the relevant literature for in-depth appreciation of the advances and issues in this field. The scientific and intellectual contributions of the students, fellows, and collaborators to the author's program is gratefully acknowledged. Program support for the author during preparation of this review was provided by the Oregon National Primate Research Center (RR00163), the Specialized Cooperative Centers Program in Reproductive Research (HD18185), and individual research grants (R01 HD20869 and WHO/Rockefeller Foundation, RF96020). A special thanks to Ms. Carol Gibbins and Mr. Joel Ito for their assistance in preparing this manuscript.
PY - 2006
Y1 - 2006
N2 - The corpus luteum-an endocrine gland in the adult ovary-is formed from the follicle wall after ovulation. It is associated with four unique features. The first is its ephemeral nature: the corpus luteum exists for a limited life span that in many species depends on the fate of the oocyte released by the antecedent ovulatory follicle. Second, its primary, if not sole essential function is to synthesize and secrete the steroid hormone, progesterone that acts in the reproductive tract to permit implantation of the early embryo in the uterine endometrium and support a maternal environment that sustains intrauterine pregnancy. Thus, the third feature of the corpus luteum is its physiological connection to viviparity. All mammals, many reptiles, and a few fishes that produce live young exhibit corpora lutea, although the essential connection between the corpus luteum and viviparity is less obvious in nonmammalian species. In some of these species, luteal function may be related to final oocyte maturation, egg movement in the oviduct, or oviposition, because the corpus luteum exists in some oviparous reptiles, amphibians, and birds as well.
AB - The corpus luteum-an endocrine gland in the adult ovary-is formed from the follicle wall after ovulation. It is associated with four unique features. The first is its ephemeral nature: the corpus luteum exists for a limited life span that in many species depends on the fate of the oocyte released by the antecedent ovulatory follicle. Second, its primary, if not sole essential function is to synthesize and secrete the steroid hormone, progesterone that acts in the reproductive tract to permit implantation of the early embryo in the uterine endometrium and support a maternal environment that sustains intrauterine pregnancy. Thus, the third feature of the corpus luteum is its physiological connection to viviparity. All mammals, many reptiles, and a few fishes that produce live young exhibit corpora lutea, although the essential connection between the corpus luteum and viviparity is less obvious in nonmammalian species. In some of these species, luteal function may be related to final oocyte maturation, egg movement in the oviduct, or oviposition, because the corpus luteum exists in some oviparous reptiles, amphibians, and birds as well.
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U2 - 10.1016/B978-012515400-0/50017-8
DO - 10.1016/B978-012515400-0/50017-8
M3 - Chapter
AN - SCOPUS:84883977065
SN - 9780125154000
SP - 475
EP - 526
BT - Knobil and Neill's Physiology of Reproduction
PB - Elsevier Inc.
ER -