Structure and regulation of calcium/calmodulin-dependent protein kinases

Thomas R. Soderling, James T. Stull

    Research output: Contribution to journalReview article

    151 Scopus citations

    Abstract

    The structure and regulation of calcium\calmodulin-dependent protein kinases (CaM-K) were discussed. The CaM-K were activated and inhibited through phosphorylation by other protein kinases. The results showed that the cross-talk with other signalling pathways allowed the integration of Ca2+ signals with other signalling pathways to modulate the physiological output of the cell.

    Original languageEnglish (US)
    Pages (from-to)2341-2351
    Number of pages11
    JournalChemical Reviews
    Volume101
    Issue number8
    DOIs
    StatePublished - Aug 1 2001

    ASJC Scopus subject areas

    • Chemistry(all)

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