Stress and immunity

Implications for viral disease and wound healing

Leigh A. Rozlog, Janice K. Kiecolt-Glaser, Phillip Marucha, John F. Sheridan, Ronald Glaser

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

It is now well established that psychological stress can downregulate the cellular immune response. Communication between the central nervous system and the immune system occurs via a complex network of bidirectional signals linking the nervous, endocrine, and immune systems. Stress disrupts the homeostasis of this network, which in turn, alters immune function. In this review, we discuss the role of stress in modulating cellular immune function and the potential health implications of this downregulation.

Original languageEnglish (US)
Pages (from-to)786-792
Number of pages7
JournalJournal of Periodontology
Volume70
Issue number7
DOIs
StatePublished - Jul 1999
Externally publishedYes

Fingerprint

Virus Diseases
Wound Healing
Immune System
Immunity
Down-Regulation
Endocrine System
Psychological Stress
Cellular Immunity
Nervous System
Homeostasis
Central Nervous System
Communication
Health

Keywords

  • Immune response
  • Stress, psychological
  • Viral diseases/pathogenesis
  • Wound healing

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Stress and immunity : Implications for viral disease and wound healing. / Rozlog, Leigh A.; Kiecolt-Glaser, Janice K.; Marucha, Phillip; Sheridan, John F.; Glaser, Ronald.

In: Journal of Periodontology, Vol. 70, No. 7, 07.1999, p. 786-792.

Research output: Contribution to journalArticle

Rozlog, LA, Kiecolt-Glaser, JK, Marucha, P, Sheridan, JF & Glaser, R 1999, 'Stress and immunity: Implications for viral disease and wound healing', Journal of Periodontology, vol. 70, no. 7, pp. 786-792. https://doi.org/10.1902/jop.1999.70.7.786
Rozlog, Leigh A. ; Kiecolt-Glaser, Janice K. ; Marucha, Phillip ; Sheridan, John F. ; Glaser, Ronald. / Stress and immunity : Implications for viral disease and wound healing. In: Journal of Periodontology. 1999 ; Vol. 70, No. 7. pp. 786-792.
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