Stereotactic body radiation therapy: An ablative treatment option for primary and secondary liver tumors

Martin Fuss, Charles Thomas

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Only a subset of patients with primary and secondary liver tumors are eligible for surgical resection because of either the presence of extrahepatic disease, increased number of hepatic lesions, the anatomical distribution of tumors within the liver, and/or general medical inoperability. Nonsurgical, ablative tumor treatment may benefit selected patients by preserving normal liver function. This review presents the concept and technology of stereotactic body radiation therapy and summarizes available clinical data describing applications in the treatment of malignant liver tumors. We present predominantly peer-reviewed data but also summarize recent clinical developments along with discussions of current ongoing and planned multicenter studies.

Original languageEnglish (US)
Pages (from-to)130-138
Number of pages9
JournalAnnals of Surgical Oncology
Volume11
Issue number2
DOIs
StatePublished - 2004
Externally publishedYes

Fingerprint

Radiotherapy
Liver
Neoplasms
Therapeutics
Multicenter Studies
Technology

Keywords

  • Hepatocellular carcinoma
  • Liver ablation
  • Liver metastasis
  • Review
  • Stereotactic body radiation therapy

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Stereotactic body radiation therapy : An ablative treatment option for primary and secondary liver tumors. / Fuss, Martin; Thomas, Charles.

In: Annals of Surgical Oncology, Vol. 11, No. 2, 2004, p. 130-138.

Research output: Contribution to journalArticle

@article{c47a5e4789ef4544a0cc342c17407385,
title = "Stereotactic body radiation therapy: An ablative treatment option for primary and secondary liver tumors",
abstract = "Only a subset of patients with primary and secondary liver tumors are eligible for surgical resection because of either the presence of extrahepatic disease, increased number of hepatic lesions, the anatomical distribution of tumors within the liver, and/or general medical inoperability. Nonsurgical, ablative tumor treatment may benefit selected patients by preserving normal liver function. This review presents the concept and technology of stereotactic body radiation therapy and summarizes available clinical data describing applications in the treatment of malignant liver tumors. We present predominantly peer-reviewed data but also summarize recent clinical developments along with discussions of current ongoing and planned multicenter studies.",
keywords = "Hepatocellular carcinoma, Liver ablation, Liver metastasis, Review, Stereotactic body radiation therapy",
author = "Martin Fuss and Charles Thomas",
year = "2004",
doi = "10.1245/ASO.2004.10.907",
language = "English (US)",
volume = "11",
pages = "130--138",
journal = "Annals of Surgical Oncology",
issn = "1068-9265",
publisher = "Springer New York",
number = "2",

}

TY - JOUR

T1 - Stereotactic body radiation therapy

T2 - An ablative treatment option for primary and secondary liver tumors

AU - Fuss, Martin

AU - Thomas, Charles

PY - 2004

Y1 - 2004

N2 - Only a subset of patients with primary and secondary liver tumors are eligible for surgical resection because of either the presence of extrahepatic disease, increased number of hepatic lesions, the anatomical distribution of tumors within the liver, and/or general medical inoperability. Nonsurgical, ablative tumor treatment may benefit selected patients by preserving normal liver function. This review presents the concept and technology of stereotactic body radiation therapy and summarizes available clinical data describing applications in the treatment of malignant liver tumors. We present predominantly peer-reviewed data but also summarize recent clinical developments along with discussions of current ongoing and planned multicenter studies.

AB - Only a subset of patients with primary and secondary liver tumors are eligible for surgical resection because of either the presence of extrahepatic disease, increased number of hepatic lesions, the anatomical distribution of tumors within the liver, and/or general medical inoperability. Nonsurgical, ablative tumor treatment may benefit selected patients by preserving normal liver function. This review presents the concept and technology of stereotactic body radiation therapy and summarizes available clinical data describing applications in the treatment of malignant liver tumors. We present predominantly peer-reviewed data but also summarize recent clinical developments along with discussions of current ongoing and planned multicenter studies.

KW - Hepatocellular carcinoma

KW - Liver ablation

KW - Liver metastasis

KW - Review

KW - Stereotactic body radiation therapy

UR - http://www.scopus.com/inward/record.url?scp=2342593284&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2342593284&partnerID=8YFLogxK

U2 - 10.1245/ASO.2004.10.907

DO - 10.1245/ASO.2004.10.907

M3 - Article

C2 - 14761915

AN - SCOPUS:2342593284

VL - 11

SP - 130

EP - 138

JO - Annals of Surgical Oncology

JF - Annals of Surgical Oncology

SN - 1068-9265

IS - 2

ER -