Static lung compliance as an index of early pulmonary disease in systematic sclerosis

A. Sud, D. Gupta, Ajay Wanchu, S. K. Jindal, P. Bambery

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Pulmonary function abnormalities constitute the most important cause of morbidity and mortality in patients with systemic sclerosis (SSc). A restrictive ventilatory defect with a reduction in pulmonary carbon monoxide diffusion capacity (DLCO) is the commonest finding. Static lung compliance (Cst) is perhaps the most sensitive parameter for the detection of abnormal pulmonary mechanics. We compared the results of Cst and DLCO in patients with SSc and normal spirometry to identify early pulmonary disease. Sixteen of 50 patients had normal spirometry, eight of whom had abnormal Cst. Four of them also had a reduced DLCO. Two patients had abnormal DLCO but their Cst was normal. One of them had pulmonary hypertension on echocardiography. We conclude that Cst was helpful in diagnosing early pulmonary abnormality in 50% of patients with normal spirometry. Among these patients Cst was a better index of abnormality than DLCO.

Original languageEnglish (US)
Pages (from-to)177-180
Number of pages4
JournalClinical Rheumatology
Volume20
Issue number3
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Lung Compliance
Sclerosis
Lung Diseases
Spirometry
Lung
Systemic Scleroderma
Carbon Monoxide
Mechanics
Pulmonary Hypertension
Echocardiography
Morbidity
Mortality

Keywords

  • Progressive systematic sclerosis
  • Pulmonary fibrosis
  • Scleroderma

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Static lung compliance as an index of early pulmonary disease in systematic sclerosis. / Sud, A.; Gupta, D.; Wanchu, Ajay; Jindal, S. K.; Bambery, P.

In: Clinical Rheumatology, Vol. 20, No. 3, 2001, p. 177-180.

Research output: Contribution to journalArticle

Sud, A. ; Gupta, D. ; Wanchu, Ajay ; Jindal, S. K. ; Bambery, P. / Static lung compliance as an index of early pulmonary disease in systematic sclerosis. In: Clinical Rheumatology. 2001 ; Vol. 20, No. 3. pp. 177-180.
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