Staging ovarian cancer

Role of imaging

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Ovarian cancer is relatively common, and often presents at an advanced stage with widespread intraperitoneal metastases. The constellation of complex pelvic masses, ascites, omental cake, and other peritoneal implants is virtually diagnostic. All patients are potential surgical candidates, since suspected early stage disease is treated by a comprehensive staging laparotomy including total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy. Operable advanced disease is treated by surgical debulking and adjuvant combination chemotherapy. The role of imaging is to detect and characterize adnexal masses as likely malignant, recognize unusual findings that may suggest atypical pathology, demonstrate metastases in order to prevent under-staging, and detect specific sites of disease that may be unresectable. These aims are directly related to clinical management; characterization of an adnexal mass as malignant guides appropriate surgical referral, recognition of atypical pathology such as malignant granulosa cell tumor in a young woman may be an indication for fertility-preserving surgery. Demonstration of metastatic sites assists surgical planning, and detection of unresectable disease may be an indication for neoadjuvant (ie, preoperative) chemotherapy with interval debulking rather than primary debulking with adjuvant (postoperative) chemotherapy.

Original languageEnglish (US)
Pages (from-to)609-636
Number of pages28
JournalRadiologic Clinics of North America
Volume40
Issue number3
DOIs
StatePublished - 2002
Externally publishedYes

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Ovarian Neoplasms
Adjuvant Chemotherapy
Pathology
Granulosa Cell Tumor
Neoplasm Metastasis
Ovariectomy
Combination Drug Therapy
Hysterectomy
Ascites
Laparotomy
Fertility
Referral and Consultation
Drug Therapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Staging ovarian cancer : Role of imaging. / Coakley, Fergus.

In: Radiologic Clinics of North America, Vol. 40, No. 3, 2002, p. 609-636.

Research output: Contribution to journalArticle

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