This case discusses the pharmacokinetic interaction between cyclosporine and St. John's wort, resulting in renal failure. Cylcosporin is a cytochrome P450 3A4 and P-glycoprotein substrate and St. John's wort is a 3A4 and P-glycoprotein inducer.
|Original language||English (US)|
|Title of host publication||A Case Approach to Perioperative Drug-Drug Interactions|
|Publisher||Springer New York|
|Number of pages||3|
|ISBN (Print)||9781461474951, 9781461474944|
|State||Published - Sep 15 2015|
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