Src family protein tyrosine kinases and cellular signal transduction pathways

Thorsten Erpel, Sara A. Courtneidge

Research output: Contribution to journalArticle

271 Scopus citations

Abstract

Members of the Src family of protein tyrosine kinases are thought to be involved in signal transduction pathways that control growth and cellular architecture. In recent years it has been shown that they interact with receptor tyrosine kinases (such as the platelet-derived growth factor receptor) and with receptors that themselves lack intrinsic tyrosine kinase activity (such as the interleukin-2 receptor). In some cases they are required for mitogenic signalling by these receptors. They are also activated in response to stress and during mitosis.

Original languageEnglish (US)
Pages (from-to)176-182
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume7
Issue number2
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Cell Biology

Fingerprint Dive into the research topics of 'Src family protein tyrosine kinases and cellular signal transduction pathways'. Together they form a unique fingerprint.

  • Cite this