Src family protein tyrosine kinases and cellular signal transduction pathways

Thorsten Erpel, Sara Courtneidge

Research output: Contribution to journalArticle

271 Citations (Scopus)

Abstract

Members of the Src family of protein tyrosine kinases are thought to be involved in signal transduction pathways that control growth and cellular architecture. In recent years it has been shown that they interact with receptor tyrosine kinases (such as the platelet-derived growth factor receptor) and with receptors that themselves lack intrinsic tyrosine kinase activity (such as the interleukin-2 receptor). In some cases they are required for mitogenic signalling by these receptors. They are also activated in response to stress and during mitosis.

Original languageEnglish (US)
Pages (from-to)176-182
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume7
Issue number2
DOIs
StatePublished - 1995
Externally publishedYes

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src-Family Kinases
Signal Transduction
Platelet-Derived Growth Factor Receptors
Interleukin-2 Receptors
Receptor Protein-Tyrosine Kinases
Mitosis
Protein-Tyrosine Kinases
Growth

ASJC Scopus subject areas

  • Cell Biology

Cite this

Src family protein tyrosine kinases and cellular signal transduction pathways. / Erpel, Thorsten; Courtneidge, Sara.

In: Current Opinion in Cell Biology, Vol. 7, No. 2, 1995, p. 176-182.

Research output: Contribution to journalArticle

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