Abstract
Background. Cinnamon aldehydes found in cinnamon-flavored gums can incite mucosal alterations at points of contact with the oral mucosa. These alterations may include inflammation and epithelial proliferation, but as a rule, the changes are reversible and promptly resolve when gum-chewing activity is discontinued. Methods. The authors report a case of a 24-year- old woman who developed a squamous cell carcinoma of the tongue following persistent and prolonged exposure to cinnamon-flavored gum. Results. Several social, clinical, and histopathologic features point to the cinnamon-flavored chewing gum as a possible causal factor in the development of the patient's oral carcinoma. Conclusions. Prompt withdrawal of cinnamon products is encouraged in heavy gum chewers who develop cinnamon-related oral lesions. For those lesions which do not promptly resolve upon cinnamon withdrawal, diagnostic biopsy should be considered to exclude the possibility of a squamous cell carcinoma.
Original language | English (US) |
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Pages (from-to) | 430-433 |
Number of pages | 4 |
Journal | Head and Neck |
Volume | 20 |
Issue number | 5 |
DOIs | |
State | Published - Aug 1998 |
Externally published | Yes |
Keywords
- Chewing gum
- Cinnamon
- Contact stomatitis
- Oral cavity
- Plasma cell gingivitis
- Squamous cell carcinoma
- Tongue
ASJC Scopus subject areas
- Otorhinolaryngology