Squamous cell carcinoma of the anal canal

Dennis L. Rousseau, Charles Thomas, Nicholas J. Petrelli, Morton S. Kahlenberg

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Squamous cell carcinoma (SCC) of the anal canal is a rare condition with increasing incidence rates in the United States population in the past several decades. This review article provides a complete overview of the etiology, anatomy and the approach to the multidisciplinary management of the patient with anal SCC. Chemoradiation therapy for the treatment of SCC of the anal canal provides excellent disease control and survival while preserving anal sphincter function in the majority of patients. The surgeon plays a key role in the diagnosis and follow-up of this disease. Surgical salvage with APR for disease persistence or recurrence in carefully selected patients can result in reasonable 5-year survivals.

Original languageEnglish (US)
Pages (from-to)121-132
Number of pages12
JournalSurgical Oncology
Volume14
Issue number3
DOIs
StatePublished - Nov 2005
Externally publishedYes

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Anal Canal
Squamous Cell Carcinoma
Survival
Anatomy
Recurrence
Incidence
Therapeutics
Population

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Rousseau, D. L., Thomas, C., Petrelli, N. J., & Kahlenberg, M. S. (2005). Squamous cell carcinoma of the anal canal. Surgical Oncology, 14(3), 121-132. https://doi.org/10.1016/j.suronc.2005.07.002

Squamous cell carcinoma of the anal canal. / Rousseau, Dennis L.; Thomas, Charles; Petrelli, Nicholas J.; Kahlenberg, Morton S.

In: Surgical Oncology, Vol. 14, No. 3, 11.2005, p. 121-132.

Research output: Contribution to journalArticle

Rousseau, DL, Thomas, C, Petrelli, NJ & Kahlenberg, MS 2005, 'Squamous cell carcinoma of the anal canal', Surgical Oncology, vol. 14, no. 3, pp. 121-132. https://doi.org/10.1016/j.suronc.2005.07.002
Rousseau, Dennis L. ; Thomas, Charles ; Petrelli, Nicholas J. ; Kahlenberg, Morton S. / Squamous cell carcinoma of the anal canal. In: Surgical Oncology. 2005 ; Vol. 14, No. 3. pp. 121-132.
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