This article traces the almost 50-year development of the generalization of the NMR timescale reciprocal called the NMR "shutter speed." This concept facilitates the measurement of rate constants of dynamic processes in equilibrium, without changing the sample temperature. It is particularly useful for intercompartmental water interchanges in living biological tissue. Spin-offs from this long quest have included shift reagents for tissue 23Na MR signals in vivo, systematization of bulk magnetic susceptibility effects in NMR, and relaxographic imaging.
ASJC Scopus subject areas
- Analytical Chemistry
- Biomedical Engineering
- Radiology Nuclear Medicine and imaging