Spermatogonial stem cell transplantation to the testis

Shaun Goodyear; Ralph Brinster

doi:10.1101/pdb.prot094235

Spermatogonial stem cell transplantation to the testis

Shaun Goodyear, Ralph Brinster

Knight Cancer Institute

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Spermatogonial stem cells (SSCs) are located in the basal region of the seminiferous tubules and provide a self-renewing reservoir from which progenitor spermatogonia arise and transiently amplify in number before transition to a differentiating state. SSC transplantation involves grafting mouse testicular cells into the seminiferous tubules of an aspermic recipient testis that is generated either by chemical (e.g., busulfan) treatment or genetic mutations.

Original language	English (US)
Pages (from-to)	299-305
Number of pages	7
Journal	Cold Spring Harbor Protocols
Volume	2017
Issue number	4
DOIs	https://doi.org/10.1101/pdb.prot094235
State	Published - Apr 2017

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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Spermatogonial stem cell transplantation to the testis

Abstract

ASJC Scopus subject areas

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