Abstract
Spermatogonial stem cells (SSCs) are located in the basal region of the seminiferous tubules and provide a self-renewing reservoir from which progenitor spermatogonia arise and transiently amplify in number before transition to a differentiating state. SSC transplantation involves grafting mouse testicular cells into the seminiferous tubules of an aspermic recipient testis that is generated either by chemical (e.g., busulfan) treatment or genetic mutations.
Original language | English (US) |
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Pages (from-to) | 299-305 |
Number of pages | 7 |
Journal | Cold Spring Harbor Protocols |
Volume | 2017 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2017 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)