Abstract
Spermatogonial stem cells (SSCs) are located in the basal region of the seminiferous tubules and provide a self-renewing reservoir from which progenitor spermatogonia arise and transiently amplify in number before transition to a differentiating state. SSC transplantation involves grafting mouse testicular cells into the seminiferous tubules of an aspermic recipient testis that is generated either by chemical (e.g., busulfan) treatment or genetic mutations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 299-305 |
| Number of pages | 7 |
| Journal | Cold Spring Harbor Protocols |
| Volume | 2017 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2017 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)