Speckle reduction in swept source optical coherence tomography images with slow-axis averaging

Ou Tan, Yan Li, Yimin Wang, Martin F. Kraus, Jonathan J. Liu, Benjamin Potsaid, Bernhard Baumann, James G. Fujimoto, David Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

The effectiveness of speckle reduction using traditional frame averaging technique was limited in ultrahigh speed optical coherence tomography (OCT). As the motion between repeated frames was very small, the speckle pattern of the frames might be identical. This problem could be solved by averaging frames acquired at slightly different locations. The optimized scan range depended on the spot size of the laser beam, the smoothness of the boundary, and the homogeneity of the tissue. In this study we presented a method to average frames obtained within a narrow range along the slow-axis. A swept-source OCT with 100,000 Hz axial scan rate was used to scan the retina in vivo. A series of narrow raster scans (0-50 micron along the slow axis) were evaluated. Each scan contained 20 image frames evenly distributed in the scan range. The imaging frame rate was 417 HZ. Only frames with high correlation after rigid registration were used in averaging. The result showed that the contrast-to-noise ratio (CNR) increased with the scan range. But the best edge reservation was obtained with 15 micron scan range. Thus, for ultrahigh speed OCT systems, averaging frames from a narrow band along the slow-axis could achieve better speckle reduction than traditional frame averaging techniques.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI
PublisherSPIE
ISBN (Print)9780819488565
DOIs
StatePublished - 2012
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI - San Francisco, CA, United States
Duration: Jan 23 2012Jan 25 2012

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8213
ISSN (Print)1605-7422

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI
CountryUnited States
CitySan Francisco, CA
Period1/23/121/25/12

Keywords

  • Contrast-to-noise Ratio
  • Frame Averaging
  • Slow-axis Averaging
  • Speckle Reduction
  • Swept Source Optical Coherence Tomography

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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