Spatial distribution of attentional modulation at columnar resolution in macaque area V4

Hisashi Tanigawa, Gang Chen, Anna Roe

Research output: Contribution to journalArticle

Abstract

Attention to a location in a visual scene affects neuronal responses in visual cortical areas in a retinotopically specific manner. Optical imaging studies have revealed that cortical responses consist of two components of different sizes: the stimulus-nonspecific global signal and the stimulus-specific mapping signal (domain activity). It remains unclear whether either or both of these components are modulated by spatial attention. In this study, to determine the spatial distribution of attentional modulation at columnar resolution, we performed cerebral blood volume (CBV)-based optical imaging in area V4 of monkeys performing a color change detection task in which spatial attention was manipulated. We found that spatial attention enhanced global signals of the hemodynamic responses, but did not affect stimulus-selective domain activities. These results indicate the involvement of global signals in neural processing of spatial attention. We propose that global signals reflect the neural substrate of the normalization pool in normalization models of attention.

Original languageEnglish (US)
Article number102
JournalFrontiers in Neural Circuits
Volume10
Issue numberDEC
DOIs
StatePublished - Dec 12 2016
Externally publishedYes

Fingerprint

Macaca
Optical Imaging
Haplorhini
Color
Hemodynamics

Keywords

  • Cerebral blood volume
  • Column
  • Global signals
  • Intrinsic signal optical imaging
  • Mapping signals
  • Normalization model
  • Spatial attention

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Sensory Systems
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

Spatial distribution of attentional modulation at columnar resolution in macaque area V4. / Tanigawa, Hisashi; Chen, Gang; Roe, Anna.

In: Frontiers in Neural Circuits, Vol. 10, No. DEC, 102, 12.12.2016.

Research output: Contribution to journalArticle

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