Solitary spinal metastasis of Hürthle cell thyroid carcinoma

Daniel M. Sciubba, Rory J. Petteys, Steven Kang, Khoi Than, Ziya L. Gokaslan, Gary L. Gallia, Jean Paul Wolinsky

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Hürthle cell carcinoma is a rare variant of differentiated thyroid cancer that occasionally forms distant metastases. However, even in the presence of metastases, patients with Hürthle cell carcinoma have a relatively good prognosis. There are few reports of Hürthle cell carcinoma metastases to the vertebral column, and none describing aggressive resection of spinal metastases. Here, we report a 68-year-old woman with a solitary metastasis of Hürthle cell carcinoma to the T1 vertebral body causing severe kyphotic deformity, myelopathy, and pain. The patient was treated with aggressive excisional decompression of the spinal cord and T1 vertebral body resection from an entirely posterior approach. Reconstruction and stabilization of the anterior spine was accomplished with a transforaminal lumbar interbody fusion allograft spacer and posterior instrumentation. We discuss aspects of the diagnosis, management, patient selection, and surgical treatment of metastatic Hürthle cell carcinoma in reference to the literature.

Original languageEnglish (US)
Pages (from-to)797-801
Number of pages5
JournalJournal of Clinical Neuroscience
Volume17
Issue number6
DOIs
StatePublished - Jun 2010
Externally publishedYes

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Thyroid Neoplasms
Neoplasm Metastasis
Carcinoma
Spine
Spinal Cord Diseases
Decompression
Patient Selection
Allografts
Spinal Cord
Pain
Therapeutics

Keywords

  • Fusion
  • Hürthle cell
  • Metastasis
  • Spine
  • Thyroid carcinoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

Cite this

Sciubba, D. M., Petteys, R. J., Kang, S., Than, K., Gokaslan, Z. L., Gallia, G. L., & Wolinsky, J. P. (2010). Solitary spinal metastasis of Hürthle cell thyroid carcinoma. Journal of Clinical Neuroscience, 17(6), 797-801. https://doi.org/10.1016/j.jocn.2009.09.039

Solitary spinal metastasis of Hürthle cell thyroid carcinoma. / Sciubba, Daniel M.; Petteys, Rory J.; Kang, Steven; Than, Khoi; Gokaslan, Ziya L.; Gallia, Gary L.; Wolinsky, Jean Paul.

In: Journal of Clinical Neuroscience, Vol. 17, No. 6, 06.2010, p. 797-801.

Research output: Contribution to journalArticle

Sciubba, DM, Petteys, RJ, Kang, S, Than, K, Gokaslan, ZL, Gallia, GL & Wolinsky, JP 2010, 'Solitary spinal metastasis of Hürthle cell thyroid carcinoma', Journal of Clinical Neuroscience, vol. 17, no. 6, pp. 797-801. https://doi.org/10.1016/j.jocn.2009.09.039
Sciubba, Daniel M. ; Petteys, Rory J. ; Kang, Steven ; Than, Khoi ; Gokaslan, Ziya L. ; Gallia, Gary L. ; Wolinsky, Jean Paul. / Solitary spinal metastasis of Hürthle cell thyroid carcinoma. In: Journal of Clinical Neuroscience. 2010 ; Vol. 17, No. 6. pp. 797-801.
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