Solitary fibrous tumors arising in abdominal wall hernia sacs

Jeffrey R. Lee, Susan M. Hancock, Robert Martindale

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Solitary fibrous tumor (SFT) of the peritoneum is an unusual spindle-cell neoplasm. SFT was originally described in the pleura; however it is now diagnosed in multiple extrathoracic sites. Most believe that the tumor is of mesenchymal origin and should be classified as a variant of fibroma. SFT of the pleura and peritoneum have also been called fibrous mesothelioma, and the cell of origin is felt to be a pluripotential submesothelial mesenchymal cell. Primary tumors arising in hernia sacs are rare, and we report on two patients with hernia SFT. The first is a 67-year-old man who had a diffusely thickened distal left inguinal hernia sac. Within the sac was copious myxoid material mimicking pseudomyxoma peritonei. Herniorrhaphy and orchiectomy were performed. The second is a 44-year-old woman with a midepigastric mass attached to a ventral hernia. Wide local excision was performed. Both tumors demonstrated plump spindle cells, one with myxoid background and the other with keloidal collagen. Calretinin immunostaining was positive in both tumors, whereas CD34 was negative. This suggests tumor origin from a submesothial pluripotential cell that maintains potential for mesothelial differentiation. Surgical excision is the treatment of choice with the degree of resectability being a powerful predictor of outcome.

Original languageEnglish (US)
Pages (from-to)577-581
Number of pages5
JournalAmerican Surgeon
Volume67
Issue number6
StatePublished - 2001
Externally publishedYes

Fingerprint

Solitary Fibrous Tumors
Abdominal Hernia
Abdominal Wall
Pleural Solitary Fibrous Tumor
Neoplasms
Peritoneum
Hernia
Pseudomyxoma Peritonei
Ventral Hernia
Calbindin 2
Fibroma
Orchiectomy
Pleura
Inguinal Hernia
Herniorrhaphy
Collagen

ASJC Scopus subject areas

  • Surgery

Cite this

Solitary fibrous tumors arising in abdominal wall hernia sacs. / Lee, Jeffrey R.; Hancock, Susan M.; Martindale, Robert.

In: American Surgeon, Vol. 67, No. 6, 2001, p. 577-581.

Research output: Contribution to journalArticle

Lee, Jeffrey R. ; Hancock, Susan M. ; Martindale, Robert. / Solitary fibrous tumors arising in abdominal wall hernia sacs. In: American Surgeon. 2001 ; Vol. 67, No. 6. pp. 577-581.
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