Small intestinal submucosa plug for closure of dilated nephrostomy tracts: A pilot study in swine

Hideyaki Kakizawa; M. J. Conlin; Dusan Pavcnik; Barry T. Uchida; Marc Loriaux; Young Hwan Kim; Frederick S. Keller; Josef Rösch

doi:10.1007/s00270-010-9811-4

Small intestinal submucosa plug for closure of dilated nephrostomy tracts: A pilot study in swine

Hideyaki Kakizawa, M. J. Conlin, Dusan Pavcnik, Barry T. Uchida, Marc Loriaux, Young Hwan Kim, Frederick S. Keller, Josef Rösch

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.

Original language	English (US)
Pages (from-to)	596-600
Number of pages	5
Journal	Cardiovascular and interventional radiology
Volume	33
Issue number	3
DOIs	https://doi.org/10.1007/s00270-010-9811-4
State	Published - Jun 2010
Externally published	Yes

Keywords

Biomaterial
Embolization
Interventional procedures
Kidneys
Small intestinal submucosa

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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title = "Small intestinal submucosa plug for closure of dilated nephrostomy tracts: A pilot study in swine",

abstract = "The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.",

keywords = "Biomaterial, Embolization, Interventional procedures, Kidneys, Small intestinal submucosa",

author = "Hideyaki Kakizawa and Conlin, {M. J.} and Dusan Pavcnik and Uchida, {Barry T.} and Marc Loriaux and Kim, {Young Hwan} and Keller, {Frederick S.} and Josef R{\"o}sch",

year = "2010",

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doi = "10.1007/s00270-010-9811-4",

language = "English (US)",

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T2 - A pilot study in swine

AU - Kakizawa, Hideyaki

AU - Conlin, M. J.

AU - Pavcnik, Dusan

AU - Uchida, Barry T.

AU - Loriaux, Marc

AU - Kim, Young Hwan

AU - Keller, Frederick S.

AU - Rösch, Josef

PY - 2010/6

Y1 - 2010/6

N2 - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.

AB - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.

KW - Biomaterial

KW - Embolization

KW - Interventional procedures

KW - Kidneys

KW - Small intestinal submucosa

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JO - CardioVascular and Interventional Radiology

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ER -

Small intestinal submucosa plug for closure of dilated nephrostomy tracts: A pilot study in swine

Abstract

Keywords

ASJC Scopus subject areas

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