TY - JOUR
T1 - Small intestinal submucosa plug for closure of dilated nephrostomy tracts
T2 - A pilot study in swine
AU - Kakizawa, Hideyaki
AU - Conlin, M. J.
AU - Pavcnik, Dusan
AU - Uchida, Barry T.
AU - Loriaux, Marc
AU - Kim, Young Hwan
AU - Keller, Frederick S.
AU - Rösch, Josef
PY - 2010/6/1
Y1 - 2010/6/1
N2 - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.
AB - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.
KW - Biomaterial
KW - Embolization
KW - Interventional procedures
KW - Kidneys
KW - Small intestinal submucosa
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U2 - 10.1007/s00270-010-9811-4
DO - 10.1007/s00270-010-9811-4
M3 - Article
C2 - 20112022
AN - SCOPUS:77953133299
VL - 33
SP - 596
EP - 600
JO - CardioVascular and Interventional Radiology
JF - CardioVascular and Interventional Radiology
SN - 7415-5101
IS - 3
ER -