Abstract
The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 596-600 |
| Number of pages | 5 |
| Journal | CardioVascular and Interventional Radiology |
| Volume | 33 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 2010 |
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Keywords
- Biomaterial
- Embolization
- Interventional procedures
- Kidneys
- Small intestinal submucosa
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine
Cite this
Small intestinal submucosa plug for closure of dilated nephrostomy tracts : A pilot study in swine. / Kakizawa, Hideyaki; Conlin, Michael; Pavcnik, Dusan; Uchida, Barry; Loriaux, Marc; Kim, Young Hwan; Keller, Frederick; Rosch, Josef.
In: CardioVascular and Interventional Radiology, Vol. 33, No. 3, 06.2010, p. 596-600.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Small intestinal submucosa plug for closure of dilated nephrostomy tracts
T2 - A pilot study in swine
AU - Kakizawa, Hideyaki
AU - Conlin, Michael
AU - Pavcnik, Dusan
AU - Uchida, Barry
AU - Loriaux, Marc
AU - Kim, Young Hwan
AU - Keller, Frederick
AU - Rosch, Josef
PY - 2010/6
Y1 - 2010/6
N2 - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.
AB - The aim of this study was to evaluate efficacy of a plug made of small intestinal submucosa (SIS) for closure of dilated nephrostomy tract in the kidney after nephroscopy. Ten kidneys in 5 swine had nephrostomy tracts dilated up to 8 mm. The SIS plug was placed into the dilated renal cortex under nephroscopic control. Follow-up arteriograms, retrograde pyelograms, and macroscopic and histologic studies at 24 h (n = 4), 6 weeks (n = 2), and 3 months (n = 4) were performed to evaluate the efficacy of the plug. The SIS plug effectively closed the dilated nephrostomy tract. Follow-up studies showed minimal changes of the kidneys, except for 1 small infarction, regarding inflammatory and foreign-body reactions and progressive scarring of the SIS. SIS plug is effective for occlusion of dilated nephrostomy tract after nephroscopy. Its efficacy should be compared with other therapeutic options.
KW - Biomaterial
KW - Embolization
KW - Interventional procedures
KW - Kidneys
KW - Small intestinal submucosa
UR - http://www.scopus.com/inward/record.url?scp=77953133299&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77953133299&partnerID=8YFLogxK
U2 - 10.1007/s00270-010-9811-4
DO - 10.1007/s00270-010-9811-4
M3 - Article
VL - 33
SP - 596
EP - 600
JO - CardioVascular and Interventional Radiology
JF - CardioVascular and Interventional Radiology
SN - 7415-5101
IS - 3
ER -