Sleep Disturbances in Traumatic Brain Injury: Associations With Sensory Sensitivity

Jonathan E. Elliott, Ryan A. Opel, Kris B. Weymann, Alex Q. Chau, Melissa A. Papesh, Megan L. Callahan, Daniel Storzbach, Miranda M. Lim

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Study Objectives: Sleep disturbances following traumatic brain injury (TBI) in Veterans are very common and often persist as chronic sequelae. In addition, sensory sensitivity, ie, discomfort upon exposure to light and noise, is common after TBI. However, the relationship between sleep disturbances and sensory sensitivity in Veterans following TBI has not yet been examined, yet both are established early markers of neurodegeneration. Methods: Veterans (n = 95) in the chronic phase of recovery from TBI at the VA Portland Health Care System completed an overnight polysomnography and provided self-report data on sensory (eg, light and noise) sensitivity, and sleep disturbances. Participants were categorized into four sensory sensitivity groups: (1) “neither,” neither light nor noise sensitivity (n = 36); (2) “light,” only light sensitivity (n = 12); (3) “noise,” only noise sensitivity (n = 24); and (4) “both,” light and noise sensitivity (n = 23). Results: Veterans with TBI reported sleep disturbances that were significantly correlated with the severity of their sensory sensitivity and associated with posttraumatic stress disorder (PTSD). Multiple linear regression revealed insomnia severity to be the strongest predictor of the relationship between sleep disturbances and sensory sensitivity. Furthermore, sensory sensitivity was associated with a higher mean heart rate during sleep, even after controlling for PTSD status. Conclusions: These data are the first to report the prevalence and association between sensory sensitivity and sleep disturbances in Veterans with TBI. These data also suggest that the underlying mechanism of the sleep-sensory relationship could be due in part to comorbid PTSD and autonomic nervous system hyperarousal.

Original languageEnglish (US)
Pages (from-to)1177-1186
Number of pages10
JournalJournal of Clinical Sleep Medicine
Volume14
Issue number7
DOIs
StatePublished - Jul 15 2018

Keywords

  • Autonomic hyperarousal
  • Light sensitivity
  • Neurodegeneration
  • Noise sensitivity
  • PTSD
  • Veterans

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Neurology
  • Clinical Neurology

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