Size matters

Research output: Contribution to journalComment/debate

1 Scopus citations

Abstract

In this issue of Blood, Yau and colleagues provide evidence that guide catheter thrombosis in patients undergoing percutaneous coronary intervention (PCI) is initiated by contact system activation, and that unfractionated heparin is more effective than fondaparinux at limiting catheter occlusions because heparinantithrombin complexes are able to target multiple points along the coagulation cascade, as opposed to the smaller fractionated heparins and heparinoids that provide higher selectivity for factor Xa.

Original languageEnglish (US)
Pages (from-to)6481-6482
Number of pages2
JournalBlood
Volume118
Issue number25
DOIs
StatePublished - Dec 15 2011

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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