Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

W. U. Mirza, I. W. Rak, V. M. Thadani, J. J. Cereghino, W. R. Garnett, L. M. Brown, Y. Zhang, G. W. Belendiuk

Research output: Contribution to journalArticle

22 Scopus citations


We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

Original languageEnglish (US)
Pages (from-to)1727-1729
Number of pages3
Issue number6
StatePublished - Dec 1998


ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Mirza, W. U., Rak, I. W., Thadani, V. M., Cereghino, J. J., Garnett, W. R., Brown, L. M., Zhang, Y., & Belendiuk, G. W. (1998). Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. Neurology, 51(6), 1727-1729.