Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

W. U. Mirza, I. W. Rak, V. M. Thadani, J. J. Cereghino, W. R. Garnett, L. M. Brown, Y. Zhang, G. W. Belendiuk

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22 Scopus citations

Abstract

We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

Original languageEnglish (US)
Pages (from-to)1727-1729
Number of pages3
JournalNeurology
Volume51
Issue number6
DOIs
StatePublished - Dec 1998

ASJC Scopus subject areas

  • Clinical Neurology

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    Mirza, W. U., Rak, I. W., Thadani, V. M., Cereghino, J. J., Garnett, W. R., Brown, L. M., Zhang, Y., & Belendiuk, G. W. (1998). Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. Neurology, 51(6), 1727-1729. https://doi.org/10.1212/WNL.51.6.1727