Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

W. U. Mirza, I. W. Rak, V. M. Thadani, James Cereghino, W. R. Garnett, L. M. Brown, Y. Zhang, G. W. Belendiuk

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

Original languageEnglish (US)
Pages (from-to)1727-1729
Number of pages3
JournalNeurology
Volume51
Issue number6
StatePublished - 1998
Externally publishedYes

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Carbamazepine
Seizures
Capsules
Multicenter Studies
Quality of Life

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Mirza, W. U., Rak, I. W., Thadani, V. M., Cereghino, J., Garnett, W. R., Brown, L. M., ... Belendiuk, G. W. (1998). Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. Neurology, 51(6), 1727-1729.

Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. / Mirza, W. U.; Rak, I. W.; Thadani, V. M.; Cereghino, James; Garnett, W. R.; Brown, L. M.; Zhang, Y.; Belendiuk, G. W.

In: Neurology, Vol. 51, No. 6, 1998, p. 1727-1729.

Research output: Contribution to journalArticle

Mirza, WU, Rak, IW, Thadani, VM, Cereghino, J, Garnett, WR, Brown, LM, Zhang, Y & Belendiuk, GW 1998, 'Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures', Neurology, vol. 51, no. 6, pp. 1727-1729.
Mirza WU, Rak IW, Thadani VM, Cereghino J, Garnett WR, Brown LM et al. Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. Neurology. 1998;51(6):1727-1729.
Mirza, W. U. ; Rak, I. W. ; Thadani, V. M. ; Cereghino, James ; Garnett, W. R. ; Brown, L. M. ; Zhang, Y. ; Belendiuk, G. W. / Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures. In: Neurology. 1998 ; Vol. 51, No. 6. pp. 1727-1729.
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