Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

W. U. Mirza; I. W. Rak; V. M. Thadani; J. J. Cereghino; W. R. Garnett; L. M. Brown; Y. Zhang; G. W. Belendiuk

doi:10.1212/WNL.51.6.1727

Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

W. U. Mirza, I. W. Rak, V. M. Thadani, J. J. Cereghino, W. R. Garnett, L. M. Brown, Y. Zhang, G. W. Belendiuk

Neurology

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We evaluated the use of a new, controlled-release capsule form of carbamazepine, Carbatrol capsules, in an open-label, multicenter study of 124 patients with complex partial seizures. Ninety-one percent of the patients successfully completed the 6-month trial with good seizure control, with a significant improvement in quality of life. We conclude that switching patients with complex partial seizures from multiple daily-dose carbamazepine to twice-daily Carbatrol on a milligram-to-milligram basis is relatively safe.

Original language	English (US)
Pages (from-to)	1727-1729
Number of pages	3
Journal	Neurology
Volume	51
Issue number	6
DOIs	https://doi.org/10.1212/WNL.51.6.1727
State	Published - Dec 1998

ASJC Scopus subject areas

Clinical Neurology

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author = "Mirza, {W. U.} and Rak, {I. W.} and Thadani, {V. M.} and Cereghino, {J. J.} and Garnett, {W. R.} and Brown, {L. M.} and Y. Zhang and Belendiuk, {G. W.}",

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AU - Rak, I. W.

AU - Thadani, V. M.

AU - Cereghino, J. J.

AU - Garnett, W. R.

AU - Brown, L. M.

AU - Zhang, Y.

AU - Belendiuk, G. W.

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Six-month evaluation of Carbatrol (extended-release carbamazepine) in complex partial seizures

Abstract

ASJC Scopus subject areas

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