Single unit recordings in the rat pineal gland: Evidence for habenulo-pineal neural connections

Research output: Contribution to journalArticle

68 Scopus citations

Abstract

Extracellular potentials were recorded in the pineal gland of urethane-anesthetized rats. Two distinct populations of excitable pineal "cells" were found, the silent "cells" which were driven by habenula stimulation and the spontaneously active cells. In the former case 17 of the responses (median latency of 1.2 ms) showed a positive-negative potential, and 6 (about 1 ms latency) showed only positive potential of 1-2 ms duration. The remaining cells (114), which could not be driven by habenula stimulation, exhibited spontaneous activity with a firing frequency from less than 1 Hz to greater than 100 Hz with a median firing frequency of 10 Hz. These experiments clearly demonstrate a direct habenulo-pineal fiber pathway and furthermore show that there are neuronal elements in the pineal which are only activated by habenula stimulation.

Original languageEnglish (US)
Pages (from-to)187-192
Number of pages6
JournalExperimental Brain Research
Volume39
Issue number2
DOIs
StatePublished - May 1 1980
Externally publishedYes

Keywords

  • Habenula stimulation
  • Habenulo-pineal pathway
  • Pineal
  • Single unit recording

ASJC Scopus subject areas

  • Neuroscience(all)

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