Simple theory, measurements, and Rules of thumb for dosimetry during photodynamic therapy

Steven L. Jacques

doi:10.1117/12.978009

Simple theory, measurements, and Rules of thumb for dosimetry during photodynamic therapy

Steven L. Jacques

Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

43 Scopus citations

Abstract

Dosimetry of laser fluence rates within a tissue are required for proper planning of photodynamic therapy at a specific site on a given individual. A simple one-dimensional theory of light penetration into tissue is presented. A device for measurement of the total reflectance and the lateral diffusion of light provides a simple means for specifying the tissue optical parameters that govern laser dosimetry. Rules of thumb for complicating factors such as narrow laser beams and optical fiber delivery are discussed.

Original language	English (US)
Pages (from-to)	100-108
Number of pages	9
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1065
DOIs	https://doi.org/10.1117/12.978009
State	Published - Jun 13 1989
Event	Photodynamic Therapy: Mechanisms 1989 - Los Angeles, United States Duration: Jan 15 1989 → Jan 20 1989

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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AB - Dosimetry of laser fluence rates within a tissue are required for proper planning of photodynamic therapy at a specific site on a given individual. A simple one-dimensional theory of light penetration into tissue is presented. A device for measurement of the total reflectance and the lateral diffusion of light provides a simple means for specifying the tissue optical parameters that govern laser dosimetry. Rules of thumb for complicating factors such as narrow laser beams and optical fiber delivery are discussed.

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Simple theory, measurements, and Rules of thumb for dosimetry during photodynamic therapy

Abstract

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