Simple optical theory for light dosimetry during PDT (Invited Paper)

Steven L. Jacques

Research output: Chapter in Book/Report/Conference proceedingConference contribution

29 Scopus citations

Abstract

Photons are one of the three major reactants in the photodynamic reaction that yields toxic photoproduct for cell killing. Dosimetry of light is a major concern when planning a photodynamic therapy (PDT) protocol. This paper presents a very simple approach toward the tissue optics with a practical conclusion about how tissue optics affects planning of day-to-day PDT dosimetry. The paper does not address all the complexities of real tissue dosimetry, such as heterogeneous tissues, variable absorption due to changing tissue blood content, and variable tissue oxygen levels. The paper outlines the optical behavior in a homogeneous tissue, which is a starting point for understanding light dosimetry.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherPubl by Int Soc for Optical Engineering
Pages155-165
Number of pages11
ISBN (Print)0819407917
StatePublished - Dec 1 1992
Externally publishedYes
EventOptical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy - Los Angeles, CA, USA
Duration: Jan 20 1992Jan 21 1992

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1645
ISSN (Print)0277-786X

Other

OtherOptical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy
CityLos Angeles, CA, USA
Period1/20/921/21/92

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Jacques, S. L. (1992). Simple optical theory for light dosimetry during PDT (Invited Paper). In Proceedings of SPIE - The International Society for Optical Engineering (pp. 155-165). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1645). Publ by Int Soc for Optical Engineering.