Simple optical theory for light dosimetry during PDT (Invited Paper)

Steven L. Jacques

Simple optical theory for light dosimetry during PDT (Invited Paper)

Steven L. Jacques

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Photons are one of the three major reactants in the photodynamic reaction that yields toxic photoproduct for cell killing. Dosimetry of light is a major concern when planning a photodynamic therapy (PDT) protocol. This paper presents a very simple approach toward the tissue optics with a practical conclusion about how tissue optics affects planning of day-to-day PDT dosimetry. The paper does not address all the complexities of real tissue dosimetry, such as heterogeneous tissues, variable absorption due to changing tissue blood content, and variable tissue oxygen levels. The paper outlines the optical behavior in a homogeneous tissue, which is a starting point for understanding light dosimetry.

Original language	English (US)
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
Publisher	Publ by Int Soc for Optical Engineering
Pages	155-165
Number of pages	11
ISBN (Print)	0819407917
State	Published - 1992
Externally published	Yes
Event	Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy - Los Angeles, CA, USA Duration: Jan 20 1992 → Jan 21 1992

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1645
ISSN (Print)	0277-786X

Other

Other	Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy
City	Los Angeles, CA, USA
Period	1/20/92 → 1/21/92

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Cite this

Simple optical theory for light dosimetry during PDT (Invited Paper). / Jacques, Steven L.
Proceedings of SPIE - The International Society for Optical Engineering. Publ by Int Soc for Optical Engineering, 1992. p. 155-165 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1645).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Jacques, SL 1992, Simple optical theory for light dosimetry during PDT (Invited Paper). in Proceedings of SPIE - The International Society for Optical Engineering. Proceedings of SPIE - The International Society for Optical Engineering, vol. 1645, Publ by Int Soc for Optical Engineering, pp. 155-165, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy, Los Angeles, CA, USA, 1/20/92.

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ER -

Simple optical theory for light dosimetry during PDT (Invited Paper)

Abstract

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ASJC Scopus subject areas

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