Simian herpesviruses and their risk to humans

Ryan D. Estep, Ilhem Messaoudi, Scott W. Wong

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations

Abstract

A high level of genetic and physiological homology with humans has rendered non-human primates (NHP) an essential animal model for biomedical research. As such NHP offer a unique opportunity to study host-pathogen interactions in a species that closely mimics human biology but can yet be maintained under tight laboratory conditions. Indeed, studies using NHP have been critical to our understanding of pathogenesis as well as the development of vaccines and therapeutics. This further facilitated by the fact that NHPs are susceptible to a variety of pathogens that bear significant homology to human pathogens. Unfortunately, these same viruses pose a potential health issue to humans. In this review we discuss the simian herpesviruses and their potential to cause disease in researchers that come into close contact with them.

Original languageEnglish (US)
Pages (from-to)B78-B84
JournalVaccine
Volume28
Issue numberSUPPL. 2
DOIs
StatePublished - May 26 2010

Keywords

  • Biosafety
  • Simian: Herpesvirus

ASJC Scopus subject areas

  • Molecular Medicine
  • Immunology and Microbiology(all)
  • veterinary(all)
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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