Simian herpesviruses and their risk to humans

Ryan Estep, Ilhem Messaoudi, Scott Wong

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A high level of genetic and physiological homology with humans has rendered non-human primates (NHP) an essential animal model for biomedical research. As such NHP offer a unique opportunity to study host-pathogen interactions in a species that closely mimics human biology but can yet be maintained under tight laboratory conditions. Indeed, studies using NHP have been critical to our understanding of pathogenesis as well as the development of vaccines and therapeutics. This further facilitated by the fact that NHPs are susceptible to a variety of pathogens that bear significant homology to human pathogens. Unfortunately, these same viruses pose a potential health issue to humans. In this review we discuss the simian herpesviruses and their potential to cause disease in researchers that come into close contact with them.

Original languageEnglish (US)
JournalVaccine
Volume28
Issue numberSUPPL. 2
DOIs
StatePublished - May 26 2010

Fingerprint

Cercopithecine Herpesvirus 1
Primates
Host-Pathogen Interactions
host-pathogen relationships
pathogens
biomedical research
vaccine development
Biomedical Research
Vaccines
pathogenesis
Animal Models
researchers
animal models
Research Personnel
Viruses
Biological Sciences
viruses
therapeutics
Health

Keywords

  • Biosafety
  • Simian: Herpesvirus

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)
  • Molecular Medicine

Cite this

Simian herpesviruses and their risk to humans. / Estep, Ryan; Messaoudi, Ilhem; Wong, Scott.

In: Vaccine, Vol. 28, No. SUPPL. 2, 26.05.2010.

Research output: Contribution to journalArticle

Estep, Ryan ; Messaoudi, Ilhem ; Wong, Scott. / Simian herpesviruses and their risk to humans. In: Vaccine. 2010 ; Vol. 28, No. SUPPL. 2.
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