Abstract
The use of growth hormone (GH) to treat short children who are clearly GH-deficient is now well accepted. However, GH treatment of short children who have no currently recognizable abnormalities in their GH-insulin-like growth factor I axis remains controversial. Whether such children with so-called idiopathic short stature (ISS) should be treated with GH was the subject of an international workshop held in St.-Paul-de-Vence, France, in April 1999. This article summarizes the issues discussed at the workshop, including the definition of ISS, ethical and health-economic aspects of treatment, results from clinical trials and surveillance studies, and the use of prediction models in aiding treatment decisions. Copyright (C) 2000 S. Karger AG, Basel.
Original language | English (US) |
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Pages (from-to) | 150-157 |
Number of pages | 8 |
Journal | Hormone Research |
Volume | 52 |
Issue number | 3 |
State | Published - Dec 1 1999 |
Keywords
- Growth
- Growth hormone
- Height, final
- Prediction model, height
- Quality of life
- Short stature, idiopathic
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology