Abstract
Staphylococcus aureus is a common cause of hospital-acquired infections and is a leading causative organism of bloodstream infection. The binding of S. aureus to activated platelet monolayers under shear conditions was studied using a parallel-plate flow chamber and epi-fluorescent videomicroscopy. Heterotypic aggregation was also studied in suspension to stimulate interaction events in the bulk flow. Shear increased the percent of platelets bound in heteroaggregates from approximately 2% for static controls to more than 10% after 2 minutes of shear exposure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S-88 |
| Journal | Annals of Biomedical Engineering |
| Volume | 28 |
| Issue number | SUPPL. 1 |
| State | Published - Dec 1 2000 |
| Externally published | Yes |
| Event | 2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA Duration: Oct 12 2000 → Oct 14 2000 |
ASJC Scopus subject areas
- Biomedical Engineering