Sex hormones and the risk of incident prostate cancer

Nicholas A. Daniels, Carrie Nielson, Andrew R. Hoffman, Douglas C. Bauer

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: To assess whether sex hormone levels are associated with subsequent development of prostate cancer. Methods: A case-cohort study was conducted within the ongoing Osteoporotic Fractures in Men cohort study of community-dwelling men 24.9 pg/dL) was nearly 4-fold higher (adjusted heart rate = 3.93, CI: 1.61-9.57). Other sex hormones were not associated with the risk of prostate cancer. Conclusions: In this cohort of older men, higher estrone levels were strongly associated with an increased risk of incident prostate cancer. This association between estrone and prostate cancer risk needs to be clarified by further study.

Original languageEnglish (US)
Pages (from-to)1034-1040
Number of pages7
JournalUrology
Volume76
Issue number5
DOIs
StatePublished - Nov 2010
Externally publishedYes

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Gonadal Steroid Hormones
Prostatic Neoplasms
Estrone
Cohort Studies
Independent Living
Osteoporotic Fractures
Heart Rate

ASJC Scopus subject areas

  • Urology

Cite this

Sex hormones and the risk of incident prostate cancer. / Daniels, Nicholas A.; Nielson, Carrie; Hoffman, Andrew R.; Bauer, Douglas C.

In: Urology, Vol. 76, No. 5, 11.2010, p. 1034-1040.

Research output: Contribution to journalArticle

Daniels, NA, Nielson, C, Hoffman, AR & Bauer, DC 2010, 'Sex hormones and the risk of incident prostate cancer', Urology, vol. 76, no. 5, pp. 1034-1040. https://doi.org/10.1016/j.urology.2010.01.086
Daniels, Nicholas A. ; Nielson, Carrie ; Hoffman, Andrew R. ; Bauer, Douglas C. / Sex hormones and the risk of incident prostate cancer. In: Urology. 2010 ; Vol. 76, No. 5. pp. 1034-1040.
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