Sex hormones and the risk of incident prostate cancer

Nicholas A. Daniels, Carrie Nielson, Andrew R. Hoffman, Douglas C. Bauer

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Objective: To assess whether sex hormone levels are associated with subsequent development of prostate cancer. Methods: A case-cohort study was conducted within the ongoing Osteoporotic Fractures in Men cohort study of community-dwelling men 24.9 pg/dL) was nearly 4-fold higher (adjusted heart rate = 3.93, CI: 1.61-9.57). Other sex hormones were not associated with the risk of prostate cancer. Conclusions: In this cohort of older men, higher estrone levels were strongly associated with an increased risk of incident prostate cancer. This association between estrone and prostate cancer risk needs to be clarified by further study.

Original languageEnglish (US)
Pages (from-to)1034-1040
Number of pages7
JournalUrology
Volume76
Issue number5
DOIs
Publication statusPublished - Nov 2010
Externally publishedYes

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ASJC Scopus subject areas

  • Urology

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