Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults

Alia L. Yasen, Jacob Raber, Jeremy K. Miller, Brian J. Piper

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The purpose of this study was to examine how sex and apolipoprotein E (APOE) genotype contribute to individual differences in spatial learning and memory. The associations of APOE genotype with neurocognitive function have been well studied among the elderly but less is known at earlier ages. Young adults (n = 169, 88 females) completed three neurocognitive tasks: mental rotation, spatial span, and Memory Island, a spatial navigation test. Males outperformed females on all three tasks: finding the hidden targets more quickly on Memory Island (Cohen’s d = 0.62) and obtaining higher scores on mental rotation (d = 0.54) and spatial span (d = 0.37). In contrast, no significant effects of APOE were observed. The identified sex differences elaborate upon past literature documenting sexually dimorphic performance on specific neurobehavioral tasks.

Original languageEnglish (US)
Pages (from-to)2219-2226
Number of pages8
JournalArchives of Sexual Behavior
Volume44
Issue number8
DOIs
StatePublished - Nov 1 2015

Fingerprint

Apolipoproteins E
Young Adult
Islands
Genotype
Individuality
Sex Characteristics
Young Adults
Polymorphism
Spatial Memory
Mental Rotation

Keywords

  • Apolipoprotein E
  • Learning
  • Memory
  • Sex differences
  • Young adults

ASJC Scopus subject areas

  • Psychology(all)
  • Arts and Humanities (miscellaneous)

Cite this

Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults. / Yasen, Alia L.; Raber, Jacob; Miller, Jeremy K.; Piper, Brian J.

In: Archives of Sexual Behavior, Vol. 44, No. 8, 01.11.2015, p. 2219-2226.

Research output: Contribution to journalArticle

Yasen, Alia L. ; Raber, Jacob ; Miller, Jeremy K. ; Piper, Brian J. / Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults. In: Archives of Sexual Behavior. 2015 ; Vol. 44, No. 8. pp. 2219-2226.
@article{0fea4f6db8044ae99c2128aedc64931c,
title = "Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults",
abstract = "The purpose of this study was to examine how sex and apolipoprotein E (APOE) genotype contribute to individual differences in spatial learning and memory. The associations of APOE genotype with neurocognitive function have been well studied among the elderly but less is known at earlier ages. Young adults (n = 169, 88 females) completed three neurocognitive tasks: mental rotation, spatial span, and Memory Island, a spatial navigation test. Males outperformed females on all three tasks: finding the hidden targets more quickly on Memory Island (Cohen’s d = 0.62) and obtaining higher scores on mental rotation (d = 0.54) and spatial span (d = 0.37). In contrast, no significant effects of APOE were observed. The identified sex differences elaborate upon past literature documenting sexually dimorphic performance on specific neurobehavioral tasks.",
keywords = "Apolipoprotein E, Learning, Memory, Sex differences, Young adults",
author = "Yasen, {Alia L.} and Jacob Raber and Miller, {Jeremy K.} and Piper, {Brian J.}",
year = "2015",
month = "11",
day = "1",
doi = "10.1007/s10508-015-0497-1",
language = "English (US)",
volume = "44",
pages = "2219--2226",
journal = "Archives of Sexual Behavior",
issn = "0004-0002",
publisher = "Springer New York",
number = "8",

}

TY - JOUR

T1 - Sex, but not Apolipoprotein E Polymorphism, Differences in Spatial Performance in Young Adults

AU - Yasen, Alia L.

AU - Raber, Jacob

AU - Miller, Jeremy K.

AU - Piper, Brian J.

PY - 2015/11/1

Y1 - 2015/11/1

N2 - The purpose of this study was to examine how sex and apolipoprotein E (APOE) genotype contribute to individual differences in spatial learning and memory. The associations of APOE genotype with neurocognitive function have been well studied among the elderly but less is known at earlier ages. Young adults (n = 169, 88 females) completed three neurocognitive tasks: mental rotation, spatial span, and Memory Island, a spatial navigation test. Males outperformed females on all three tasks: finding the hidden targets more quickly on Memory Island (Cohen’s d = 0.62) and obtaining higher scores on mental rotation (d = 0.54) and spatial span (d = 0.37). In contrast, no significant effects of APOE were observed. The identified sex differences elaborate upon past literature documenting sexually dimorphic performance on specific neurobehavioral tasks.

AB - The purpose of this study was to examine how sex and apolipoprotein E (APOE) genotype contribute to individual differences in spatial learning and memory. The associations of APOE genotype with neurocognitive function have been well studied among the elderly but less is known at earlier ages. Young adults (n = 169, 88 females) completed three neurocognitive tasks: mental rotation, spatial span, and Memory Island, a spatial navigation test. Males outperformed females on all three tasks: finding the hidden targets more quickly on Memory Island (Cohen’s d = 0.62) and obtaining higher scores on mental rotation (d = 0.54) and spatial span (d = 0.37). In contrast, no significant effects of APOE were observed. The identified sex differences elaborate upon past literature documenting sexually dimorphic performance on specific neurobehavioral tasks.

KW - Apolipoprotein E

KW - Learning

KW - Memory

KW - Sex differences

KW - Young adults

UR - http://www.scopus.com/inward/record.url?scp=84947037774&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84947037774&partnerID=8YFLogxK

U2 - 10.1007/s10508-015-0497-1

DO - 10.1007/s10508-015-0497-1

M3 - Article

C2 - 25750133

AN - SCOPUS:84947037774

VL - 44

SP - 2219

EP - 2226

JO - Archives of Sexual Behavior

JF - Archives of Sexual Behavior

SN - 0004-0002

IS - 8

ER -