Severe virilization in a girl with a steroid cell tumor of the ovary

David Snyder, Stephen Lafranchi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We report a 6 year-old girl with striking signs of virilization, as well as elevated concentrations of testosterone and 17-hydroxyprogesterone. Although the elevated 17-hydroxyprogesterone concentration initially suggested late-onset 21-hydroxylase deficiency, she was found to have an ovarian mass by sonography which at surgery proved to be a hilus cell subtype of steroid cell tumor. This intra-ovarian tumor appears to be the smallest tumor of its type ever reported. The testosterone concentration was normal three days after tumor resection and has remained so two years later.

Original languageEnglish (US)
Pages (from-to)221-224
Number of pages4
JournalJournal of Pediatric Endocrinology and Metabolism
Volume12
Issue number2
StatePublished - 1999

Fingerprint

Virilism
Ovary
Steroids
17-alpha-Hydroxyprogesterone
Testosterone
Neoplasms
Ultrasonography

Keywords

  • Hilus cell tumor
  • Ovarian tumor
  • Steroid cell tumor
  • Virilization

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health

Cite this

Severe virilization in a girl with a steroid cell tumor of the ovary. / Snyder, David; Lafranchi, Stephen.

In: Journal of Pediatric Endocrinology and Metabolism, Vol. 12, No. 2, 1999, p. 221-224.

Research output: Contribution to journalArticle

Snyder, David ; Lafranchi, Stephen. / Severe virilization in a girl with a steroid cell tumor of the ovary. In: Journal of Pediatric Endocrinology and Metabolism. 1999 ; Vol. 12, No. 2. pp. 221-224.
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