Serum human chorionic gonadotropin decline following aspiration abortion in early pregnancy less than 42 days gestation

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To define serum human chorionic gonadotropin (hCG) decline following complete aspiration abortion. Study Design: We performed a secondary analysis of 86 patients who underwent uncomplicated aspiration abortion for ultrasound-confirmed pregnancy ≤42 days gestation and had serum hCG at the time of aspiration and within 3 days postprocedure. Results: Median hCG declines were 72.9% by day 1 (n = 14), 87.6% by day 2 (n = 50), and 92.8% by day 3 (n = 22). Ninetieth percentile declines were 67.8%, 81.5%, and 90.8%. Minimum hCG declines were 56.2%, 77.3%, and 83.2%. Trends did not vary by gestational age or by initial hCG <3000 mIU/mL. Conclusion: Postprocedure hCG trend varies over the first few days in early gestation. At ≤42 days gestation, serial hCG decline at 1 day after completed aspiration abortion is greater than 50%, consistent with the decline observed in medication abortion. Implications: This study confirms previously estimated human chorionic gonadotropin decline after aspiration abortion of at least 50% at 24 hours for completed procedure in very early gestations. Minimum declines on days 2 and 3 are approximately 70% and 80%.

Original languageEnglish (US)
Pages (from-to)113-115
Number of pages3
JournalContraception
Volume103
Issue number2
DOIs
StatePublished - Feb 2021

Keywords

  • Abortion
  • Aspiration abortion
  • Early abortion
  • Human chorionic gonadotropin
  • hCG

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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